A7856
Acipimox
≥99% (TLC)
Sinónimos:
2-Carboxy-5-methylpyrazine 4-oxide, 5-Methylpyrazinecarboxylic acid 4-oxide
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About This Item
Fórmula empírica (notación de Hill):
C6H6N2O3
Número de CAS:
Peso molecular:
154.12
Número CE:
Número MDL:
Código UNSPSC:
12352205
NACRES:
NA.79
Productos recomendados
Nivel de calidad
Ensayo
≥99% (TLC)
Formulario
powder
color
off-white to faint yellow
mp
177-180 °C
temp. de almacenamiento
2-8°C
cadena SMILES
[n+]1(c(cncc1C(=O)O)C)[O-]
InChI
1S/C6H6N2O3/c1-4-2-7-3-5(6(9)10)8(4)11/h2-3H,1H3,(H,9,10)
Clave InChI
DNRXJHATQULEHC-UHFFFAOYSA-N
Categorías relacionadas
Acciones bioquímicas o fisiológicas
Acipimox, also known as olbemox, is a nicotinic acid analog. It functions as an anti-lipolytic drug and vasodilator. Acipimox may be used in various metabolic studies involving insulin and ghrelin. It lowers total cholesterol and total triglycerides, which helps in the treatment of hyperlipidemia.
Niacin-derived, vasodilator studied for its lipid-lowering effect.
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
dust mask type N95 (US), Eyeshields, Gloves
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Sebastiaan Hammer et al.
American journal of physiology. Endocrinology and metabolism, 295(3), E714-E718 (2008-07-17)
Short-term caloric restriction increases plasma levels of nonesterified fatty acids (NEFAs) and is associated with increased myocardial triglyceride (TG) content and decreased myocardial function in healthy subjects. Whether this flexibility of myocardial TG stores and myocardial function is also present
Massimo Scacchi et al.
European journal of endocrinology, 163(2), 201-206 (2010-05-13)
The diagnosis of GH deficiency (GHD) in obese patients is complicated by the reduced GH secretion associated with overweight. A GH response to GHRH+arginine lower than 4.2 microg/l is currently considered indicative of GHD in obesity. The aim of the
Lars C Gormsen et al.
European journal of endocrinology, 154(5), 667-673 (2006-04-29)
Concentrations of the orexigenic peptide ghrelin is affected by a number of hormones, which also affect circulating levels of free fatty acids (FFAs). The present study was therefore designed to determine the direct effect of FFAs on circulating ghrelin. Eight
Jara Nedvidkova et al.
Regulatory peptides, 167(1), 134-139 (2011-01-18)
Ghrelin is predominantly produced by the stomach and the growth hormone (GH)-ghrelin feedback loop between the stomach and the pituitary gland has recently been suggested. The disruption of the gut-brain axis might be involved in bulimia nervosa (BN). We investigated
Effect of the antilipolytic nicotinic acid analogue acipimox on whole-body and skeletal muscle glucose metabolism in patients with non-insulin-dependent diabetes mellitus.
Vaag A, et al.
The Journal of Clinical Investigation, 88(4), 1282-1290 (1991)
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