A5376

Acetylsalicylic acid

≥99.0%

• Sinónimos: 2-Acetoxybenzoic acid, O-Acetylsalicylic acid, ASA, Aspirin
• Fórmula lineal: 2-(CH₃CO₂)C₆H₄CO₂H
• Número de CAS: 50-78-2
• Peso molecular: 180.16
• Beilstein: 779271
• Número CE: 200-064-1
• Número MDL: MFCD00002430
• Código UNSPSC: 12352106
• ID de la sustancia en PubChem: 24278218
• NACRES: NA.21

Propiedades

• origen biológico: synthetic
• Nivel de calidad: 200
• Ensayo: ≥99.0%
• Formulario: powder
• color: white
• pKa (25 °C): 3.5
• mp: 134-136 °C (lit.)
• solubilidad: H₂O: 10 mg/mL at 37 °C(lit.); H₂O: 3 mg/mL at 25 °C(lit.); ethanol: 50 mg/mL; aqueous base: decomposes
• ε (coeficiente de extinción): 190 at 298 nm in aqueous base at 1 mM; 409 at 231 nm in aqueous base at 1 mM; 466 at 230 nm in aqueous acid at 1 mM; 68 at 278 nm in aqueous acid at 1 mM
• cadena SMILES: CC(=O)Oc1ccccc1C(O)=O
• InChI: 1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)
• Clave InChI: BSYNRYMUTXBXSQ-UHFFFAOYSA-N
• Información sobre el gen: human ... ITGA2B(3674) , ITGB3(3690) , PTGS1(5742) , PTGS2(5743)

Descripción

Descripción general

Acetylsalicylic acid is an organic compound commonly referred to as aspirin. It works by blocking the production of compounds in the body that cause pain, swelling, and fever. Acetylsalicylic acid also serves a vital function in preventing blood clots from forming in the arteries. In research, acetylsalicylic acid is studied for its role in oxidative stress, and in cancer research as a biomarker.

Acciones bioquímicas o fisiológicas

Blocks the production of prostaglandins by inhibiting cyclooxygenase (prostaglandin H synthase), with greater selectivity toward the COX-1 isoform. The antithrombotic effect is due to the inhibition of COX-1 in platelets that blocks thromboxane production and platelet aggregation. Chemopreventive against colorectal and other solid tumors.

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H302
• Consejos de prudencia: P264 - P270 - P301 + P312 - P501
• Clasificaciones de peligro: Acute Tox. 4 Oral
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): 482.0 °F
• Punto de inflamabilidad (°C): 250 °C
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Faceshields, Gloves