39286

Hydroxystilbamidine bis(methanesulfonate)

suitable for fluorescence, ≥96.0% (HPLC)

• Sinónimos: 2-Hydroxystilbene-4,4′-dicarboxamidine bis(methanesulfonate), Fluoro-Gold
• Fórmula empírica (notación de Hill): C₁₈H₂₄N₄O₇S₂
• Número CAS: 223769-64-0
• Peso molecular: 472.54
• NACRES: NA.32
• PubChem Substance ID: 57649893
• UNSPSC Code: 41116100
• MDL number: MFCD01863083

Propiedades

• Quality Segment: 100
• assay: ≥96.0% (HPLC)
• form: powder
• fluorescence: λ_ex 318 nm; λ_em 560 nm in TBE Buffer
• suitability: suitable for fluorescence
• storage temp.: 2-8°C
• SMILES string: CS(O)(=O)=O.CS(O)(=O)=O.NC(=N)c1ccc(cc1)\C=C\c2ccc(cc2O)C(N)=N
• InChI: 1S/C16H16N4O.2CH4O3S/c17-15(18)12-5-2-10(3-6-12)1-4-11-7-8-13(16(19)20)9-14(11)21;2*1-5(2,3)4/h1-9,21H,(H3,17,18)(H3,19,20);2*1H3,(H,2,3,4)/b4-1+;;
• InChI key: YGNSQKCULHSJDC-HFPMQDOPSA-N

Descripción

General description

Hydroxystilbamidine bis (methanesulfonate), also known as Fluoro-Gold, is a retrograde fluorescent tracer. Chemically, Hydroxystilbamidine is a weak base and can cross cell membranes in its uncharged form.

A few properties of Hydroxystilbamidine bis (methanesulfonate) are:

• Intense Fluorescence.
• Extensive filling of dendrites.
• High Resistance to fading.
• No uptake by undamaged fibers.
• No diffusion from labelled cells.
• Highly compatible with other neuro-histochemical techniques.

Application

Hydroxystilbamidine bis(methanesulfonate), a fluorescent retrograde tracer (axonal transport), is used for neural mapping in microanatomical research.

Hydroxystilbamidine bis (methanesulfonate) or Fluoro-Gold (FG) is used to label neurons and investigate the early effects of hearing loss. It is used to study morphological features of extensive axonal projections within the CNS by labelling the cells.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves