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118R-1

Sigma-Aldrich

CD38 (SP149) Rabbit Monoclonal Antibody

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

100
500

conjugado

unconjugated

forma del anticuerpo

culture supernatant

tipo de anticuerpo

primary antibodies

clon

SP149, monoclonal

descripción

For In Vitro Diagnostic Use in Select Regions (See Chart)

Formulario

buffered aqueous solution

reactividad de especies

human

envase

vial of 0.1 mL concentrate (118R-14)
vial of 0.5 mL concentrate (118R-15)
bottle of 1.0 mL predilute (118R-17)
vial of 1.0 mL concentrate (118R-16)
bottle of 7.0 mL predilute (118R-18)

fabricante / nombre comercial

Cell Marque®

técnicas

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotipo

IgG

control

bone marrow, lymph node, plasma cell myeloma

Condiciones de envío

wet ice

temp. de almacenamiento

2-8°C

visualización

cytoplasmic

Información sobre el gen

human ... CD38(952)

Categorías relacionadas

Descripción general

CD38 molecule is a 46-kDa type-II transmembrane glycoprotein with a short N-terminalcytoplasmic tail (20 amino acids) and a long extracellular domain (256 amino acids). Itis present on many hematopoietic cells, especially plasma cells, and in some solid tumortissues. CD38 is one of the early expressed markers of mature naive B-cell activation and it isuseful in identifying functional mature B-lymphocyte subsets.

Calidad


IVD
IVD
IVD
RUO

Ligadura / enlace

CD38 Positive Control Slides, Product No. 118S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparación

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Otras notas

For Technical Service please contact: 800-665-7284 or email: [email protected]

Información legal

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Certificados de análisis (COA)

Lot/Batch Number
0000414508
0000414494
0000414494
0000414508
0000399647

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Flavius Martin et al.
Nature reviews. Immunology, 2(5), 323-335 (2002-05-30)
Recent advances in genomics and proteomics, combined with the facilitated generation and analysis of transgenic and gene-knockout animals, have revealed new complexities in classical biological systems, including the B-cell compartment. Studies on an 'old', but poorly characterized, B-cell subset--the naive
Kikkeri N Naresh et al.
British journal of haematology, 154(6), 770-776 (2011-07-02)
Distinguishing Burkitt lymphoma (BL) from B cell lymphoma, unclassifiable with features intermediate between diffuse large B-cell lymphoma (DLBCL) and BL (DLBCL/BL), and DLBCL is challenging. We propose an immunohistochemistry and fluorescent in situ hybridization (FISH) based scoring system that is
Sandeep S Dave et al.
The New England journal of medicine, 354(23), 2431-2442 (2006-06-09)
The distinction between Burkitt's lymphoma and diffuse large-B-cell lymphoma is crucial because these two types of lymphoma require different treatments. We examined whether gene-expression profiling could reliably distinguish Burkitt's lymphoma from diffuse large-B-cell lymphoma. Tumor-biopsy specimens from 303 patients with
Fabio Malavasi et al.
Physiological reviews, 88(3), 841-886 (2008-07-16)
The membrane proteins CD38 and CD157 belong to an evolutionarily conserved family of enzymes that play crucial roles in human physiology. Expressed in distinct patterns in most tissues, CD38 (and CD157) cleaves NAD(+) and NADP(+), generating cyclic ADP ribose (cADPR)
Leoncini, L et al. Burkitt lymphoma. In Swerdlow SH, et al. eds. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. IARC, WHO Press, Lyon, France, 2008; 262-264.
Leoncini, L
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissue, 262-264 (2008)
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