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S0882

Sigma-Aldrich

Sodium selenate

≥95% (elemental analysis)

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About This Item

Fórmula lineal:
Na2SeO4
Número de CAS:
13410-01-0
Peso molecular:
188.94
Número CE:
236-501-8
Número MDL:
MFCD00003490
Código UNSPSC:
12352302
ID de la sustancia en PubChem:
329824181
NACRES:
NA.55

grado

for analytical purposes

Nivel de calidad

200

Ensayo

≥95% (elemental analysis)

Formulario

powder or crystals

pH

5.5-7.5 (25 °C, 18.9 g/L)

cadena SMILES

[Na+].[Na+].[O-][Se]([O-])(=O)=O

InChI

1S/2Na.H2O4Se/c;;1-5(2,3)4/h;;(H2,1,2,3,4)/q2*+1;/p-2

Clave InChI

MHQOTKLEMKRJIR-UHFFFAOYSA-L

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Aplicación


  • Selenium nanoparticles alleviate ischemia reperfusion injury-induced acute kidney injury by modulating GPx-1/NLRP3/Caspase-1 pathway.: This study demonstrates that selenium nanoparticles, including sodium selenate, mitigate acute kidney injury caused by ischemia reperfusion. The nanoparticles modulate key pathways, offering potential therapeutic applications in renal injury treatment (Wang et al., 2022).

  • Phosphoproteomic profiling of selenate-treated Alzheimer′s disease model cells.: This research provides a detailed phosphoproteomic profile of Alzheimer′s disease model cells treated with sodium selenate, uncovering its effects on protein phosphorylation and implications for neuroprotection (Chen et al., 2014).

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Irrit. 2 - STOT RE 2

Código de clase de almacenamiento

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
BCCL4484
BCCK3757
BCCH0626
BCCH7647
BCCF0410

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W C Stewart et al.
Journal of animal science, 90(2), 577-584 (2011-10-04)
Adequate Se transfer from ewes to lambs is important to prevent Se-deficiency diseases. To evaluate how different chemical forms of Se administered at comparative dosages to mature ewes affect Se status of their lambs, 240 ewes were divided into 8
Nigel C Jones et al.
Neurobiology of disease, 45(3), 897-901 (2011-12-21)
Tau hyperphosphorylation has been implicated in the pathogenesis of a variety of forms of human epilepsy. Here we investigated whether treatment with sodium selenate, a drug which reduces pathological hyperphosphorylated tau by enhancement of PP2A activity, would inhibit seizures in
N M Corcoran et al.
British journal of cancer, 103(4), 462-468 (2010-07-22)
Angiogenesis is fundamental to the progression of many solid tumours including prostate cancer. Sodium selenate is a small, water-soluble, orally bioavailable activator of PP2A phosphatase with anti-angiogenic properties. This was a dose-escalation phase I study in men with asymptomatic, chemotherapy-naïve
Janet van Eersel et al.
Proceedings of the National Academy of Sciences of the United States of America, 107(31), 13888-13893 (2010-07-21)
Alzheimer's disease (AD) brains are characterized by amyloid-beta-containing plaques and hyperphosphorylated tau-containing neurofibrillary tangles (NFTs); however, in frontotemporal dementia, the tau pathology manifests in the absence of overt amyloid-beta plaques. Therapeutic strategies so far have primarily been targeting amyloid-beta, although
J A Hall et al.
Journal of animal science, 90(2), 568-576 (2011-10-04)
Although the essentiality of dietary Se for sheep has been known for decades, the chemical source and Se dosage for optimal health remain unclear. In the United States, the Food and Drug Administration (FDA) regulates Se supplementation, regardless of the
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