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Merck

Y0000259

Diclazuril for system suitability

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

2,6-Dichloro-α-(4-chlorophenyl)-4-[4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl]benzeneacetonitrile

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About This Item

Fórmula empírica (notación de Hill):
C17H9Cl3N4O2
Número de CAS:
Peso molecular:
407.64
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

diclazuril

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Clc1ccc(cc1)C(C#N)c2c(Cl)cc(cc2Cl)N3N=CC(=O)NC3=O

InChI

1S/C17H9Cl3N4O2/c18-10-3-1-9(2-4-10)12(7-21)16-13(19)5-11(6-14(16)20)24-17(26)23-15(25)8-22-24/h1-6,8,12H,(H,23,25,26)

InChI key

ZSZFUDFOPOMEET-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Diclazuril for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

pictograms

Health hazard

signalword

Warning

Hazard Classifications

Repr. 2 - STOT RE 2

target_organs

Lungs,Liver,lymph node

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2


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H W Peek et al.
Avian diseases, 50(3), 434-439 (2006-10-17)
Twenty European Eimeria spp. field isolates were subjected to an anticoccidial sensitivity test (AST). The anticoccidial drugs tested were diclazuril (Clinacox) and monensin (Elancoban). The assay was performed in a battery cage trial. Infected medicated birds were compared with an
C Le Sueur et al.
Parasitology research, 104(5), 1157-1162 (2008-12-17)
A field study was conducted to evaluate the effect of a single oral treatment with 20 mg/kg body weight (BW) of toltrazuril (Baycox 5% suspension)--TOL--in comparison to a single oral treatment with 1 mg/kg BW of diclazuril (Vecoxan suspension orale
H C Mundt et al.
Parasitology research, 100(2), 401-411 (2006-10-19)
The efficacies of 20 mg/kg body weight (BW) of toltrazuril (Toltra) 2 days post-infection (dpi), 2 mg/kg BW of diclazuril 2 and 3 dpi and 200 mg/kg BW of sulphadimidine 2, 3 and 4 dpi were compared in a model
Zuhao Shi et al.
Se pu = Chinese journal of chromatography, 27(3), 303-307 (2009-10-07)
The effects of four pretreatment methods (acetonitrile extraction-evaporation concentration, acetonitrile extraction-solid phase extraction (SPE), matrix solid-phase dispersion (MSPD) extraction and MSPD-SPE) for the simultaneous analysis of diclazuril and toltrazuril residues in chicken tissues were compared. The average recovery of 70%
Xiaojiong Shen et al.
Veterinary parasitology, 185(2-4), 290-295 (2011-11-15)
Eimeria tenella (E. tenella) is one of the most virulent pathogens of coccidiosis. In apicomplexan parasites, Hsp90 (Heat shock protein 90) is essential for the invasion and survival in host cells. In this study, the effect of diclazuril, an effective

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