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Merck

P4272

Sigma-Aldrich

3-(2-Pyridyl)-5,6-di(2-furyl)-1,2,4-triazine-5′,5′′-disulfonic acid disodium salt

Powder or crystals

Sinónimos:

5,5′-[3-(2-Pyridyl)-1,2,4-triazine-5,6-diyl]difuran-2-sulfonic acid disodium salt

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About This Item

Fórmula empírica (notación de Hill):
C16H8N4Na2O8S2
Número de CAS:
Peso molecular:
494.37
Beilstein/REAXYS Number:
5710932
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

product name

3-(2-Pyridyl)-5,6-di(2-furyl)-1,2,4-triazine-5′,5′′-disulfonic acid disodium salt, Suitable for determination of Fe

Quality Level

form

powder or crystals

composition

Water: ≤ 13.0%

Carbon (Theory), anhydrous: 38.87%

Nitrogen (Theory), anhydrous: 11.33%

color

white to dark yellow

solubility

water: 50 mg/mL, clear to slightly hazy

cation traces

C: 38.87% ((Theory), anhydrous)
N: 11.33% ((Theory), anhydrous)

suitability

suitable for determination of iron

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Na+].[Na+].[O-]S(=O)(=O)c1ccc(o1)-c2nnc(nc2-c3ccc(o3)S([O-])(=O)=O)-c4ccccn4

InChI

1S/C16H10N4O8S2.2Na/c21-29(22,23)12-6-4-10(27-12)14-15(11-5-7-13(28-11)30(24,25)26)19-20-16(18-14)9-3-1-2-8-17-9;;/h1-8H,(H,21,22,23)(H,24,25,26);;/q;2*+1/p-2

InChI key

IVLSEFOVPQFJBB-UHFFFAOYSA-L

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General description

3-(2-Pyridyl)-5,6-di(2-furyl)-1,2,4-triazine-5′,5′′-disulfonic acid disodium salt, also known as Ferene, is commonly used to measure the concentration of iron ions in aqueous solutions. The reagent is sensitive to ferrous iron ions (Fe2+) and forms a purple-colored complex with these ions in the presence of a reducing agent. The intensity of the purple color formed is proportional to the concentration of iron ions present in a solution and is quantified spectrophotometrically.

Application

3-(2-Pyridyl)-5,6-di(2-furyl)-1,2,4-triazine-5′,5′′-disulfonic acid disodium salt has been used as a component in a sensitive colorimetric assay (ferene-s assay) for the detection of iron.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Los clientes también vieron

Interaction between bovine control materials and the ferene iron method.
H M Barbour et al.
Annals of clinical biochemistry, 30 ( Pt 2), 221-222 (1993-03-01)
S Eskelinen et al.
Scandinavian journal of clinical and laboratory investigation, 43(5), 453-455 (1983-09-01)
Ferene-S was tested as the iron chromogen and the results were compared with the chromogen Ferrozine. With Ferene-S the volume of serum could be halved. We also tried to adapt Ferene-S in total iron binding capacity determinations but failed. From
British journal of haematology, 75(4), 615-616 (1990-08-01)
Certain modifications to the previously published ICSH recommendations (1978) have been approved by the Iron Panel of the International Committee for Standardization in Haematology (ICSH). They include substitution of the chromogen bathophenanthroline sulphonate with ferrozine or ferene, which are more
Novel chromogen for serum iron determinations.
T Higgins
Clinical chemistry, 27(9), 1619-1620 (1981-09-01)
J M Gutteridge
Journal of trace elements and electrolytes in health and disease, 5(4), 271-272 (1991-12-01)
Superoxide and hydrogen peroxide are often ascribed iron reducing roles in reactions leading to the formation of an aggressive oxidant by Fenton Chemistry. Hydrogen peroxide, however, does not appear to reduce iron in Fenton reactions, and we here show that

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