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Merck

M1650000

Metil 4-hidroxibenzoato

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

Éster metílico del ácido p-hidroxibenzoico, Metil parabeno, NIPAGIN

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About This Item

Fórmula lineal:
HOC6H4CO2CH3
Número de CAS:
Peso molecular:
152.15
Beilstein:
509801
Número MDL:
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
NACRES:
NA.24

grado

pharmaceutical primary standard

familia API

parabens

fabricante / nombre comercial

EDQM

mp

125-128 °C (lit.)

aplicaciones

pharmaceutical (small molecule)

Formato

neat

cadena SMILES

COC(=O)c1ccc(O)cc1

InChI

1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3

Clave InChI

LXCFILQKKLGQFO-UHFFFAOYSA-N

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, has been developed and issued under the Authority of the Issuing Pharmacopoeia.

For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia. Their suitability for any other use is not guaranteed and is the sole responsibility of the user. This standard is not intended for human or animal use.
Established for use according to European Pharmacopoeia for the preparation of the below-given solutions:
  • Reference solutions (a) and (b) in the identification, testing for related substances, and assay of methyl parahydroxybenzoate and sodium methyl parahydroxybenzoate, according to the monographs 0409 and 1262
  • Reference solution (c) for the testing of related substances in nifuroxazide using liquid chromatography (2.2.29), according to the monograph 1999
  • Reference solution (b) in the identification of sodium ethyl parahydroxybenzoate using thin-layer chromatography (General text 2.2.27), according to the monograph 2134

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

Pictogramas

Environment

Frases de peligro

Consejos de prudencia

Clasificaciones de peligro

Aquatic Chronic 2

Código de clase de almacenamiento

13 - Non Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

334.4 °F

Punto de inflamabilidad (°C)

168 °C


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Certificados de análisis (COA)

Lot/Batch Number

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Visite la Librería de documentos

Nifuroxazide
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 3363-3364 (2017)
Methyl parahydroxybenzoate
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 6180-6181 (2022)
Sodium Ethyl Parahydroxybenzoate
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 3816-3817 (2017)
Sodium Methyl Parahydroxybenzoate
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 3830-3831 (2017)
Gabriela Oliveira et al.
International journal of pharmaceutics, 435(1), 38-49 (2012-05-29)
Simple topical formulations which include volatile components, such as gels or sprays, are appealing from a cosmetic perspective. However, complex formulation effects may result from the use of volatile excipients in topical formulations, particularly when applied at clinically relevant doses

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