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A0420000

Aminocaproic acid

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

6-Aminocaproic acid, ε-Aminocaproic acid, 6-Aminohexanoic acid, EACA

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About This Item

Fórmula lineal:
H2N(CH2)5CO2H
Número de CAS:
60-32-2
Peso molecular:
131.17
Beilstein:
906872
Número MDL:
MFCD00008238
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329770612
NACRES:
NA.24

grado

pharmaceutical primary standard

familia API

aminocaproic acid

fabricante / nombre comercial

EDQM

mp

207-209 °C (dec.) (lit.)

aplicaciones

pharmaceutical (small molecule)

Formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

NCCCCCC(O)=O

InChI

1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)

Clave InChI

SLXKOJJOQWFEFD-UHFFFAOYSA-N

Información sobre el gen

human ... PLAT(5327) , PLG(5340)

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Aminocaproic acid EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Acciones bioquímicas o fisiológicas

Lysine analog. Promotes rapid dissociation of plasmin, thereby inhibiting the activation of plasminogen and subsequent fibrinolysis.
Lysine analog. Promotes rapid dissociation of plasmin, thereby inhibiting the activation of plasminogen and subsequent fibrinolysis. Reported to inhibit plasminogen binding to activated platelets. An early report indicated that it inhibits the activation of the first component of the complement system. Binds and inactivates Carboxypeptidase B.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

Producto relacionado

Referencia del producto
Descripción
Precios

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

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Allergic contact dermatitis due to epsilon-aminocaproic acid: a case report and mini-review of the published work.
Yuriko Yamamoto et al.
The Journal of dermatology, 40(4), 301-303 (2013-02-13)
G Manjunath et al.
Clinical nephrology, 58(1), 63-67 (2002-07-27)
Epsilon-aminocaproic acid (EACA) is a potent anti-fibrinolytic agent that is used in the treatment of excessive bleeding resulting from a systemic fibrinolytic state. It can also be used to treat hematuria through its action on decreasing urinary fibrinolysis. A broad
Blood-sparing drugs: aprotinin, tranexamic acid, and epsilon-aminocaproic acid.
D Royston
International anesthesiology clinics, 33(1), 155-179 (1995-01-01)
Are antifibrinolytic agents effective in the treatment of aneurysmal subarachnoid hemorrhage?
Travis R Eastin et al.
Annals of emergency medicine, 64(6), 658-659 (2014-06-24)
O N Lucas et al.
Oral surgery, oral medicine, and oral pathology, 51(2), 115-120 (1981-02-01)
On the basis of our review of the literature, it can be concluded that the advantages of E-A.C.A. include (1) safe execution of oral surgical procedures in persons with hemophilia of varying degrees of severity, (2) decrease or total elimination
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