901990

Tetrazine-acid

• Sinónimos: 4-(1,2,4,5-Tetrazin-3-yl)benzeneacetic acid
• Fórmula empírica (notación de Hill): C₁₀H₈N₄O₂
• Número de CAS: 1380500-92-4
• Peso molecular: 216.20
• Número MDL: MFCD24503098
• Código UNSPSC: 12352106
• NACRES: NA.22

Propiedades

• Formulario: powder or crystals
• disponibilidad: available only in USA
• temp. de almacenamiento: −20°C
• cadena SMILES: n1ncnnc1c2ccc(cc2)CC(=O)O
• InChI: 1S/C10H8N4O2/c15-9(16)5-7-1-3-8(4-2-7)10-13-11-6-12-14-10/h1-4,6H,5H2,(H,15,16)
• Clave InChI: SLJKKTFIAUAYGR-UHFFFAOYSA-N

Descripción

Aplicación

Tetrazine-acid demonstrates exceptionally fast cycloaddition kinetics with trans-cyclooctene (TCO) as the dienophile (up to 30,000 M^-1 s^-1). These have been the fastest kinetics reported for a bio orthogonal reaction. The chemical stability of tetrazines is substantially lower compared to methyltetrazines, thus requiring more careful selection of reagents and conditions for chemical transformation. However, tetrazine chemistry is still in an acceptable range for many applications.

Información de seguridad

• Pictogramas: GHS02
• Palabra de señalización: Danger
• Frases de peligro: H242
• Consejos de prudencia: P210 - P234 - P235 - P240 - P370 + P378 - P403
• Clasificaciones de peligro: Self-react. C
• Código de clase de almacenamiento: 5.2 - Organic peroxides and self-reacting hazardous materials
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable