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Merck

63560

Millipore

D-Manitol

ACS reagent, ≥99.0%, suitable for microbiology

Sinónimos:

manitol

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About This Item

Fórmula empírica (notación de Hill):
C6H14O6
Número de CAS:
Peso molecular:
182.17
Beilstein/REAXYS Number:
1721898
EC Number:
MDL number:
UNSPSC Code:
41106212
PubChem Substance ID:
NACRES:
NA.74

grade

ACS reagent

Quality Level

assay

≥99.0% (sum of enantiomers, HPLC)
≥99.0%

form

powder

optical activity

[α]20/D +24.0±1° in borax solution acc. to ACS

ign. residue

≤0.01% (as SO4)

loss

≤0.05% loss on drying, 20 °C (HV)

mp

165-169 °C
167-170 °C (lit.)

solubility

H2O: 0.1 g/mL, clear, colorless

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

As: ≤0.1 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg
heavy metals: ≤5 ppm (by ICP-OES)

application(s)

microbiology

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1

InChI key

FBPFZTCFMRRESA-KVTDHHQDSA-N

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General description

D-Mannitol is a hexose present in plants, bacteria, algae, and fungi.

Application

D-Mannitol has been used as a component of soya flour mannitol (SFM) medium for culturing Streptomyces.

Biochem/physiol Actions

D-Mannitol finds application in the food and pharmaceutical industry. The interaction of mannitol with neutrophils and monocytes is correlated to the upregulation of immune markers. Mannitol acts as a free-radical scavenger and may be beneficial during ischemia-reperfusion injury. It possesses osmotic diuretic properties and may help in managing cerebral edema and high intracranial pressure (ICP).
Un alditol edulcorante. Utilizado en estudios de inhibición del dulzor.

Other Notes

Important starting material for the synthesis of many chiral building blocks.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

ppe

Eyeshields, Gloves, type N95 (US)


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Los clientes también vieron

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Determination of Oxygen Respiration Rates in Wetted Developmentally Arrested Spores of Streptomyces Species
Fischer M, et al.
Bio-protocol, 4(12) (4)
S. Hanessian
Total Synthesis of Natural Products: The Chiron Approach (1983)
Matthias Turina et al.
Inflammation, 31(2), 74-83 (2007-10-25)
D-Mannitol is a substance widely used for both clinical applications as a strong diuretic and in basic research as a purportedly inert osmotic control substance. However, recent experiments have shown that mannitol is able to decrease neutrophil apoptosis in vitro
Mannitol: a review of its clinical uses
Shawkat H, et al.
Continuing education in anaesthesia, critical care & pain, 12(2) (12)
Y. Le Merrer et al.
Tetrahedron Letters, 26, 319-319 (1985)

Artículos

Culture media provides a habitat with suitable nutrients, energy sources, and certain environmental conditions for the growth of microorganisms. The components of the culture media range from simple sugars to peptones, salts, antibiotics, and complex indicators.

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