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33984

Supelco

Difloxacin hydrochloride

VETRANAL®, analytical standard

Sinónimos:

6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methylpiperazino)-4-oxo-3-quinolinecarboxylic acid hydrochloride

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About This Item

Fórmula empírica (notación de Hill):
C21H19F2N3O3 · HCl
Número de CAS:
91296-86-5
Peso molecular:
435.85
Número MDL:
MFCD03840489
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329754722
NACRES:
NA.24

grado

analytical standard

Nivel de calidad

100

Línea del producto

VETRANAL®

caducidad

limited shelf life, expiry date on the label

técnicas

HPLC: suitable
gas chromatography (GC): suitable

aplicaciones

forensics and toxicology
pharmaceutical (small molecule)

Formato

neat

cadena SMILES

Cl.CN1CCN(CC1)c2cc3N(C=C(C(O)=O)C(=O)c3cc2F)c4ccc(F)cc4

InChI

1S/C21H19F2N3O3.ClH/c1-24-6-8-25(9-7-24)19-11-18-15(10-17(19)23)20(27)16(21(28)29)12-26(18)14-4-2-13(22)3-5-14;/h2-5,10-12H,6-9H2,1H3,(H,28,29);1H

Clave InChI

JFMGBGLSDVIOHL-UHFFFAOYSA-N

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Aplicación

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Información legal

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
BCCL6741
BCCJ9159
BCBZ3498
BCBW9471

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PHR1452

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Enrofloxacin ≥99.0%

Sigma-Aldrich

17849

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Oxolinic acid analytical standard

Supelco

67126

Oxolinic acid

Tadalafil ≥98% (HPLC)

Sigma-Aldrich

SML1877

Tadalafil

Metronidazole VETRANAL®, analytical standard

Supelco

46461

Metronidazole

β-HCH PESTANAL®, analytical standard

Supelco

33376

β-HCH

Tetracycline hydrochloride VETRANAL®, analytical standard

Supelco

31741

Tetracycline hydrochloride

Marc Lamshöft et al.
The Science of the total environment, 408(7), 1563-1568 (2009-12-22)
The persistence of sulfadiazine, difloxacin, and their metabolites has been investigated in stored manure. The manure collected from sulfadiazine ((14)C-SDZ) and difloxacin ((14)C-DIF) treated pigs contained N-acetylsulfadiazine (Ac-SDZ), 4-hydroxy-SDZ (4-OH-SDZ), and sarafloxacin (SARA) as the main metabolites, respectively along with
H Z Ding et al.
Journal of veterinary pharmacology and therapeutics, 31(3), 200-204 (2008-05-13)
Pharmacokinetics of difloxacin, a fluoroquinolone antibiotic, was determined in pigs and broilers after intravenous (i.v.), intramuscular (i.m.), or oral (p.o.) administration at a single dose of five (pigs) or 10 mg/kg (broilers). Plasma concentration profiles were analyzed by a compartmental
Gui Hong Fu et al.
Environmental toxicology and pharmacology, 31(2), 307-313 (2011-07-27)
Cytochrome P450s (CYPs) play a prominent role in drug metabolism and biotransformation which are distributed in liver of aquatic animals. However, limited information is available about CYP genes involved in drug metabolism in fish. In the present study, we explore
Irina Gerchman et al.
Veterinary microbiology, 131(3-4), 266-276 (2008-06-07)
Monitoring of susceptibility to antibiotics in field isolates of pathogenic avian mycoplasmas is important for appropriate choice of treatment. Our study compared in vitro susceptibility to enrofloxacin and difloxacin in recent (2005-2006) isolates of Mycoplasma gallisepticum and Mycoplasma synoviae from
K Abo-El-Sooud et al.
Veterinary journal (London, England : 1997), 179(2), 282-286 (2008-07-08)
Single-dose disposition kinetics of difloxacin (5mg/kg bodyweight) were determined in clinically normal male dromedary camels (n=6) following intravenous (IV) and intramuscular (IM) administration. Difloxacin concentrations were determined by high performance liquid chromatography with fluorescence detection. The concentration-time data were analysed
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