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Merck

33576

Supelco

Microcystin-YR solution

10 μg/mL in methanol, analytical standard

Sinónimos:

Algae bloom standard, Biotoxin, Cyanobacterial toxin

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About This Item

Fórmula empírica (notación de Hill):
C52H72N10O13
Número de CAS:
Peso molecular:
1045.19
EC Number:
UNSPSC Code:
41116107
NACRES:
NA.24

grade

analytical standard

Quality Level

shelf life

limited shelf life, expiry date on the label

concentration

10 μg/mL in methanol

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

environmental

format

single component solution

storage temp.

−20°C

SMILES string

CO[C@@H](Cc1ccccc1)[C@@H](C)\C=C(C)\C=C\[C@@H]2NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](C)[C@@H](NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](C)NC(=O)C(=C)N(C)C(=O)CC[C@@H](NC(=O)[C@H]2C)C(O)=O)C(O)=O

InChI

1S/C52H72N10O13/c1-28(25-29(2)41(75-8)27-34-13-10-9-11-14-34)16-21-37-30(3)44(65)59-39(50(71)72)22-23-42(64)62(7)33(6)47(68)56-32(5)46(67)60-40(26-35-17-19-36(63)20-18-35)49(70)61-43(51(73)74)31(4)45(66)58-38(48(69)57-37)15-12-24-55-52(53)54/h9-11,13-14,16-21,25,29-32,37-41,43,63H,6,12,15,22-24,26-27H2,1-5,7-8H3,(H,56,68)(H,57,69)(H,58,66)(H,59,65)(H,60,67)(H,61,70)(H,71,72)(H,73,74)(H4,53,54,55)/b21-16+,28-25+/t29-,30-,31-,32+,37-,38-,39+,40-,41-,43+/m0/s1

InChI key

OWHASZQTEFAUJC-GJRPNUFSSA-N

General description

Microcystin-YR is a microcystin that is generally produced by cyanobacteria.

Application

Microcystin-YR may be used as an analytical reference standard for the quantification of the analyte in water samples using high-performance liquid chromatography with diode array detection (HPLC-DAD).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

51.8 °F

flash_point_c

11 °C

ppe

Eyeshields, Faceshields, Gloves


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Li-hong Yin et al.
Wei sheng yan jiu = Journal of hygiene research, 35(2), 162-164 (2006-06-09)
To optimize the solid-phase extraction method of isolation, purification and determination of intracellular microcystin-RR, -YR and -LR (MC-RR,-YR,-LR), algal samples were collected from Dianshan Lake, which is a major water source of Shanghai. During extraction, Algal samples were treated with
Paula Kujbida et al.
Toxicon : official journal of the International Society on Toxinology, 51(7), 1274-1280 (2008-04-15)
Microcystins (MC), a family of heptapeptide toxins produced by some genera of Cyanobacteria, have potent hepatotoxicity and tumor-promoting activity. Leukocyte infiltration in the liver was observed in MC-induced acute intoxication. Although the mechanisms of hepatotoxicity are still unclear, neutrophil infiltration
Douglas O Mountfort et al.
Toxicon : official journal of the International Society on Toxinology, 45(2), 199-206 (2005-01-01)
Depending on the class of microcystin the protein phosphatase inhibition assay shows different sensitivities to different classes of toxin. We have determined that the IC50 values obtained from dose-response curves for the inhibition of the enzyme by micro-cystin LR, nodularin
Some comments on the determination of microcystin toxins in waters by high-performance liquid chromatography.
Moollan WR, et al.
Analyst, 121(2), 233-238 (1996)
Juan L Acero et al.
Water research, 39(8), 1628-1638 (2005-05-10)
Blooms of cyanobacteria can give rise to the production of toxins which contaminate drinking water sources. Among the oxidants and disinfectants typically applied in waterworks, chlorine has been found to be effective for the degradation of microcystins. In the present

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