15527

Glicina

meets analytical specification of Ph. Eur., BP, USP, 99-101% (based on anhydrous substance)

• Sinónimos: Glicocola, Ácido aminoacético, Ácido aminoetanoico
• Fórmula lineal: NH₂CH₂COOH
• Número de CAS: 56-40-6
• Peso molecular: 75.07
• Beilstein: 635782
• Número CE: 200-272-2
• Número MDL: MFCD00008131
• Código UNSPSC: 12352209
• eCl@ss: 32160406
• ID de la sustancia en PubChem: 57647473
• NACRES: NA.21

Propiedades

• Nivel de calidad: 200
• Ensayo: 99-101% (based on anhydrous substance)
• Formulario: crystalline powder
• calidad: meets analytical specification of Ph. Eur., BP, USP
• técnicas: IR spectroscopy: suitable
• impurezas: hydrolyzable substances, complies; organic volatile impurities, complies (GC); residual solvents, complies; ≤0.001% heavy metals (as Pb); ≤1.0% ninhydrin-positive substances
• residuo de ign.: ≤0.1% (as SO₄)
• pérdida: ≤0.2% loss on drying, 105 °C, 2 h
• color: white
• pH: 5.9-6.4 (20 °C, 5%)
• pKa (25 °C): (1) 2.35, (2) 9.60; 2.35
• mp: 240 °C (dec.) (lit.)
• solubilidad: H₂O: soluble 25 gm in 100 ml at 25 degrees c; H₂O: soluble 39.1 gm in 100 ml at 50 degrees c; alcohol: soluble 0.06 gm in 100 gm (Absolute); pyridine: soluble 164 parts; alcohol: very slightly soluble; diethyl ether: very slightly soluble
• trazas de anión: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• idoneidad: complies for appearance of solution; complies for reaction against H₂SO₄; in accordance for identity (IR)
• cadena SMILES: NCC(O)=O
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
• Clave InChI: DHMQDGOQFOQNFH-UHFFFAOYSA-N
• Información sobre el gen: rat ... Grin2a(24409)

Descripción

Aplicación

Glycine was used for preparing platelets from whole-blood samples and study the stimulation of cytokine expression in leukocytes. It was used for biochemical and tolerance tests.

Acciones bioquímicas o fisiológicas

Neurotransmisor inhibidor de la médula espinal, regulador alostérico de los receptores NMDA.

Glycine has a pivotal role in lowering the plasma lipid levels in diabetic and obese patients by activating the CNS. During brain hypoxia glycine can stabilize the energetics disturbances in brain mitochondria. It also increases the in vitro development of porcine blastocysts when used along with glucose.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)