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Merck

MSSACCEPT0R-M

96 well Collection Plate

Sinónimos:

96-Well Collection Plate

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UNSPSC Code:
41104923
NACRES:
NB.13
eCl@ss:
32039006
Material:
PTFE plate (PTFE), white plate
Sterility:
non-sterile
Manufacturer/tradename:
MultiScreen®
Packaging:
pkg of 1 collection plate
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material

PTFE plate (PTFE), white plate

sterility

non-sterile

usage

Manual

packaging

pkg of 1 collection plate

manufacturer/tradename

MultiScreen®

technique(s)

parallel artificial membrane permeation assay (PAMPA): suitable

plate size

96 wells

compatibility

manifold only

General description

Increasing drug candidate predictability earlier in the discovery pipeline using non-cell-based assays can improve candidate throughput during the ADME stage. Non-cell-based permeability assays are predictive models for oral absorption of development candidates.

MultiScreen Permeability, MultiScreen-IP, and MultiScreen Acceptor plates support artificial membrane strategies for predicting passive transport.

Membranes have uniform pore structure and density for reliable transport:
- Individual wells minimize candidate cross-talk
- Compatibility with automated liquid handling systems increases throughput

Permeability Assay:
- The MultiScreen Permeability plate has a polycarbonate membrane, which supports a hexane/hexadecane artificial layer for permeability assays.1

PAMPA Assay:
- The MultiScreen-IP plate has a hydrophobic PVDF membrane, which supports a lipid bilayer for PAMPA asays.2,3

MultiScreen Acceptor Plate:
- The MultiScreen Acceptor plate can be used with either plate to capture passively transported compounds. Constructed of 100% PTFE, the plate can improve LC/MS results depending on the charge of the small molecules being evaluated.

Application

Non-Sterile, reusable, sturdy device made of PTFE, acceptor plate for PAMPA assays, 1 plate
Research Category
Nucleic acid|Protein

Physical form

Color Code:Not Applicable

Other Notes

Automation Compatible:Yes

Legal Information

MULTISCREEN is a registered trademark of Merck KGaA, Darmstadt, Germany


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