Saltar al contenido
Merck
Todas las fotos(1)

Documentos clave

EZHGIP

Millipore

Human GIP ELISA Kit

measures and quantify total GIP levels in 20 μL serum, plasma or cell culture samples

Sinónimos:

Gastric inhibitory polypeptide, Glucose-dependent insulinotropic polypeptide, Incretin hormone

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(1)

About This Item

Código UNSPSC:
12161503
eCl@ss:
32161000
NACRES:
NA.32

Nombre del producto

Human GIP (total) ELISA, This Human GIP (total) ELISA is used to measure & quantify GIP levels in Metabolism & Endocrine research.

Nivel de calidad

200

reactividad de especies

human

envase

kit of 1 × 96 wells

Parámetros

20 μL sample volume (4hr assay)

assay range

accuracy: 86.7%
linearity: 99.9%
sensitivity: 8.2 pg/mL
standard curve range: 8.2-2000 pg/mL

técnicas

ELISA: suitable

entrada

sample type cell culture supernatant
sample type serum
sample type plasma (K2 EDTA)

Nº de acceso NCBI

NM_002070.2

Nº de acceso UniProt

P04899

aplicaciones

research use

método de detección

colorimetric (450nm/590nm)

Condiciones de envío

wet ice

temp. de almacenamiento

2-8°C

Información sobre el gen

human ... GNAI2(2771)

Descripción general

GIP, also known as a gastric inhibitory polypeptide, or glucose-dependent insulinotropic polypeptide is encoded by the gene mapped to human chromosome 17q12-q21. It is synthesized in and secreted from K cells in the intestinal epithelium. GIP secretion from the gastrointestinal tract plays a major role in glucose homeostasis. It stimulates insulin secretion from pancreatic β cells after oral ingestion of nutrients. In addition, GIP also promotes insulin biosynthesis, and β-cell proliferation and alleviates beta-cell apoptosis GIP also aids in fat metabolism by stimulating triglyceride synthesis in adipocytes. Elevated levels of GIP may lead to obesity and hyperinsulinemia. This Human GIP (total) ELISA is used to measure & quantify GIP levels in Metabolism & Endocrine research.

Aplicación

Human GIP (total) ELISA has been used to measure total glucose-dependent insulinotropic polypeptide (GIP) in blood samples.

Otras notas

Research Sub Category Obesity Metabolic Disorders Room temperature, 3.5 hour assay, 20 µL sample volume, serum, plasma, or tissue culture medium Research Category Metabolism

Cláusula de descargo de responsabilidad

For research use only. Not for use in diagnostic procedures.

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Met. Corr. 1 - Skin Sens. 1

Código de clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

L A Anderson et al.
Genomics, 17(3), 618-623 (1993-09-01)
To facilitate the positional cloning of the breast-ovarian cancer gene BRCA1, we constructed a high-density genetic map of the 8.3-cM interval between D17S250 and GIP on chromosome 17q12-q21. Markers were mapped by linkage in the CEPH and in extended kindreds
Tsuyoshi Yanagimachi et al.
Molecular metabolism, 6(2), 226-231 (2017-02-10)
Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) possess multiple bioactive isoforms that are rendered non-insulinotropic by the enzyme dipeptidyl peptidase-4 (DPP-4). Recently, some ELISA kits have been developed to specifically measure "active" GIP and GLP-1, but it is unclear
Colesevelam improves oral but not intravenous glucose tolerance by a mechanism independent of insulin sensitivity and ?-cell function.
Anna L Marina,Kristina M Utzschneider,Lorena A Wright,Brenda K Montgomery et al.
Diabetes Care null
Dietary sugars stimulate fatty acid synthesis in adults.
Elizabeth J Parks, Lauren E Skokan, Maureen T Timlin, Carlus S Dingfelder
The Journal of Nutrition null
Frank Isken et al.
American journal of physiology. Endocrinology and metabolism, 295(2), E350-E355 (2008-05-29)
Menopause and premature gonadal steroid deficiency are associated with increases in fat mass and body weight. Ovariectomized (OVX) mice also show reduced locomotor activity. Glucose-dependent-insulinotropic-polypeptide (GIP) is known to play an important role both in fat metabolism and locomotor activity.
Ver todos los artículos relacionados

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico