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Key Documents

AB9040

Sigma-Aldrich

Anti-Nerve Growth Factor Antibody, pro

serum, Chemicon®

Sinónimos:

proNGF

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat, human, mouse

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... NTF3(4908)

Specificity

Reacts with proNGF.

Immunogen

Recombinant protein from mouse proNGF.

Application

Anti-Nerve Growth Factor Antibody, pro is an antibody against Nerve Growth Factor for use in IP, WB, IH.
Research Category
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins
Western blot: 1:250-1:500. Reacts with bands of 30 kD and 32 kD.

Immunohistochemistry: 1:250 on frozen sections.

Immunocytochemistry

Immunoprecipitation

Optimal working dilutions must be determined by the end user.

Physical form

Rabbit serum. Liquid.

Storage and Stability

Maintain at -20°C in undiluted for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Francesca Malerba et al.
Frontiers in molecular neuroscience, 9, 63-63 (2016-08-19)
The homeostasis between mature neurotrophin NGF and its precursor proNGF is thought to be crucial in physiology and in pathological states. Therefore, the measurement of the relative amounts of NGF and proNGF could serve as a footprint for the identification
Fangfang Gao et al.
Scientific reports, 8(1), 8135-8135 (2018-05-29)
The neurotrophic tyrosine kinase receptor TrkA (NTRK1) and its ligand nerve growth factor (NGF) are emerging promoters of tumor progression. In lung cancer, drugs targeting TrkA are in clinical trials, but the clinicopathological significance of TrkA and NGF, as well
Christopher W Rowe et al.
Scientific reports, 10(1), 1539-1539 (2020-02-01)
Nerves are emerging regulators of cancer progression and in several malignancies innervation of the tumour microenvironment is associated with tumour aggressiveness. However, the innervation of thyroid cancer is unclear. Here, we investigated the presence of nerves in thyroid cancers and
Christopher W Rowe et al.
International journal of molecular sciences, 20(23) (2019-11-30)
Metastases in thyroid cancer are associated with aggressive disease and increased patient morbidity, but the factors driving metastatic progression are unclear. The precursor for nerve growth factor (proNGF) is increased in primary thyroid cancers, but its expression or significance in
Jay Pundavela et al.
The American journal of pathology, 184(12), 3156-3162 (2014-10-07)
Nerve infiltration is essential to prostate cancer progression, but the mechanism by which nerves are attracted to prostate tumors remains unknown. We report that the precursor of nerve growth factor (proNGF) is overexpressed in prostate cancer and involved in the

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