AB1891

Anti-C-X-X-X-C Chemokine Receptor 1 Antibody, extracellular loop

Chemicon^®, from rabbit

• Sinónimos: CX3CR1
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• reactividad de especies: human
• fabricante / nombre comercial: Chemicon^®
• técnicas: immunohistochemistry: suitable; western blot: suitable
• Nº de acceso NCBI: NM_001337.3
• Nº de acceso UniProt: P49238
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... CX3CR1(1524)

Descripción

Descripción general

CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively (1-4). The seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1 (5). Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by facktokine (6). CX3CR1 mediates leukocyte migration and adhesion.

Inmunógeno

Synthetic peptide from the extracellular loop of human CX3CR1.

Aplicación

Anti-C-X-X-X-C Chemokine Receptor 1 Antibody, extracellular loop is an antibody against C-X-X-X-C Chemokine Receptor 1 for use in IH & WB.

Western blot: 1:500 (THP cell lysate can be used as positive control and an approximately 50 kDa band can be detected)

Immunohistochemistry in frozen sections

Optimal working dilutions must be determined by end user.

Forma física

Format: Purified

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable