654085

TTNPB

A synthetic stilbene analog of retinoic acid that acts as a potent retinoic acid receptor (RAR) agonist (EC50 = 21 nM, 4.0 nM, and 2.4 nM for RARα, RARβ, and RARγ, respectively).

• Sinónimos: TTNPB, 4-[(E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]benzoic Acid
• Fórmula empírica (notación de Hill): C₂₄H₂₈O₂
• Número CAS: 71441-28-6
• Peso molecular: 348.48
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD00673917
• Assay: ≥98% (HPLC)
• Form: solid
• Storage condition: OK to freeze, protect from light

Propiedades

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, protect from light
• color: white
• solubility: DMSO: 5 mg/mL
• shipped in: ambient
• storage temp.: 2-8°C
• SMILES string: OC(=O)c1ccc(cc1)\C=C(/C)\c2cc3c(cc2)C(CCC3(C)C)(C)C
• InChI: 1S/C24H28O2/c1-16(14-17-6-8-18(9-7-17)22(25)26)19-10-11-20-21(15-19)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14+
• InChI key: FOIVPCKZDPCJJY-JQIJEIRASA-N

Descripción

General description

A synthetic stilbene analog of retinoic acid which acts as a potent retinoic acid receptor (RAR) agonist (EC₅₀ = 21 nM, 4.0 nM, and 2.4 nM for RAR_α, RAR_β and RAR_γ, respectively).

Other Notes

Standeven, A.M., et al. 1996. Toxicol. Appl. Pharmacol. 138, 169.
Beard, R.L., et al. 1995. J.Med. Chem. 38, 2820.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Carcinogenic / Teratogenic (D)

Información de seguridad

• Pictogramas: GHS08,GHS07
• Palabra de advertencia: Danger
• Códigos de peligro: H315,H319,H335,H360
• Indicaciones de precaución: P202 - P261 - P264 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
• Órganos diana: Respiratory system
• Clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• ¿Qué está pasando?: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable