648480

Troponin I, Human Heart

• Sinónimos: Troponin I, Human Heart, hcTnI
• Número de CAS: 77108-40-8
• Número MDL: MFCD00213059
• Código UNSPSC: 12352202
• NACRES: NA.32

Propiedades

• Ensayo: ≥95% (SDS-PAGE)
• Nivel de calidad: 100
• Formulario: lyophilized
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze
• solubilidad: urea/Tris buffer (0.02 M Tris, HCl, pH 7.5, 7 M urea, 5 mM EDTA, 15 mM 2-mercaptoethanol): 1 mg/mL
• Condiciones de envío: ambient
• temp. de almacenamiento: −20°C

Descripción

Descripción general

Native troponin I purified from human heart. Inhibitory subunit of troponin that binds to actin in the absence of Ca²⁺, thus inhibiting the ATPase activity of actomyosin. Presence of hcTnI in plasma has been used for early detection of myocardial infarction. Useful as a standard in immunoassay and as an immunogen for antisera production. Also useful as a tracer for iodination.

Advertencia

Toxicity: Standard Handling (A)

Forma física

Lyophilized from 10 mM HCl.

Nota de preparación

Prepared from tissue of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitución

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Otras notas

Falahati, A., et al. 1999. Am. Heart J. 137, 332.
Mangano, D.T. 1994. Anesthesiology 81, 1317.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany