347436

GGACK

An irreversible inhibitor of urokinase (IC₅₀ 1 µM) and Factor Xa.

• Sinónimos: GGACK, Glu-Gly-Arg-chloromethyl Ketone
• Fórmula empírica (notación de Hill): C₁₄H₂₅ClN₆O₅
• Peso molecular: 392.84
• UNSPSC Code: 12352200
• NACRES: NA.77

Propiedades

• Quality Level: 100
• assay: ≥80% (HPLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated (hygroscopic)
• color: white
• solubility: water: 50 mg/mL
• shipped in: ambient
• storage temp.: −20°C

Descripción

General description

An irreversible inhibitor of urokinase (IC₅₀<1 µM) and Factor Xa.

Biochem/physiol Actions

Cell permeable: no

Primary Target
urokinase

Product does not compete with ATP.

Reversible: no

Target IC₅₀: <1 µM against urokinase

Warning

Toxicity: Standard Handling (A)

Sequence

H-Glu-Gly-Arg-CMK

Reconstitution

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C. Avoid freeze/thaw cycles of stock solution.

Other Notes

Kettner, C., and Shaw, E. 1979. Biochim. Biophys. Acta569, 31.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable