189482

Autocamtide-2 Related Inhibitory Peptide, Myristoylated

≥97% (HPLC), CaM kinase II inhibitor, lyophilized

• Sinónimos: Autocamtide-2 Related Inhibitory Peptide, Myristoylated, Myristoylated AIP, Myr-N-KKALRRQGAVDAL-OH
• Fórmula empírica (notación de Hill): C₇₈H₁₄₂N₂₂O₂₀
• Peso molecular: 1708.10
• UNSPSC Code: 12352202
• NACRES: NA.77
• Assay: ≥97% (HPLC)
• Form: lyophilized
• Storage condition: OK to freeze, desiccated (hygroscopic)

Propiedades

• Nombre del producto: Autocamtide-2 Related Inhibitory Peptide, Myristoylated, The Autocamtide-2 Related Inhibitory Peptide, Myristoylated controls the biological activity of calmodulin-dependent protein kinase II. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
• Quality Segment: 100
• assay: ≥97% (HPLC)
• form: lyophilized
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, desiccated (hygroscopic)
• solubility: water: 1 mg/mL
• shipped in: ambient
• storage temp.: −20°C

Descripción

General description

This peptide corresponds to AIP (Cat. No. 189480 ) which has been myristoylated at the N-terminus, thus enhancing its cell-permeability.

Biochem/physiol Actions

Cell permeable: yes

Primary Target
Calmodulin-Dependent Protein Kinase (CaM Kinase)-2

Product does not compete with ATP.

Reversible: no

Target IC₅₀: 40 nM against cam Kinase-2

Physical form

Supplied as a trifluoroacetate salt.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Gailly, P., et al. 1998. Cell Calcium 24, 293.
Ishida, A., and Fujisawa, H. 1995. J. Biol. Chem.270, 2163.
Ishida, A., et al. 1995. Biochem. Biophys. Res. Commun.212, 806.

Myr-N-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable