06-890
Anti-HDAC3 Antibody
Upstate®, from rabbit
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Productos recomendados
biological source
rabbit
Quality Level
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
mouse, human, rat
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... HDAC3(8841)
Specificity
HDAC3
Immunogen
peptide corresponding to amino acids 411-428 of human HDAC3 (NEFYDGDHDNDKESDVEI)
Application
Anti-HDAC3 Antibody is a Rabbit Polyclonal Antibody for detection of HDAC3 also known as histone deacetylase 3 & has been tested in WB.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Histones
Histones
Quality
routinely evaluated by immunoblot on a HeLa RIPA cell lysate
Target description
49kDa
Physical form
Format: Purified
Protein A chromatography
of 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Storage and Stability
2 years at -20°C
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Referencia del producto
Descripción
Precios
Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Y Zeng et al.
The Journal of biological chemistry, 273(44), 28921-28930 (1998-10-24)
Histone deacetylase-2 (HDAC2) is a component of a complex that mediates transcriptional repression in mammalian cells. A mouse HDAC2 cDNA was used to identify several recombinant clones containing the entire mouse HDAC2 gene. The mouse HDAC2 gene spans over 36
Histone acetylation and transcriptional regulatory mechanisms.
Struhl, K
Genes & Development, 12, 599-606 (1998)
Specific targeting and constitutive association of histone deacetylase complexes during transcriptional repression
Li, J., et al
Genes & Development, 16, 687-692 (2002)
Stephanie M Kyle et al.
Human molecular genetics, 25(14), 3029-3041 (2016-06-12)
Rett syndrome (RTT; OMIM 312750), a progressive neurological disorder, is caused by mutations in methyl-CpG-binding protein 2 (MECP2; OMIM 300005), a ubiquitously expressed factor. A genetic suppressor screen designed to identify therapeutic targets surprisingly revealed that downregulation of the cholesterol
K Nakade et al.
Cell death and differentiation, 14(8), 1398-1405 (2007-04-28)
Among the events that control cellular differentiation, the acetylation of histones plays a critical role in the regulation of transcription and the modification of chromatin. Jun dimerization protein 2 (JDP2), a member of the AP-1 family, is an inhibitor of
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