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Merck

C-051

Supelco

Caffeine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Número de CAS:
Número CE:
Número MDL:
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
NACRES:
NA.24

grado

certified reference material

Nivel de calidad

Formulario

liquid

Características

SNAP-N-SPIKE®, SNAP-N-SHOOT®

envase

ampule of 1 mL

fabricante / nombre comercial

Cerilliant®

concentración

1.0 mg/mL in methanol

técnicas

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

aplicaciones

forensics and toxicology

Formato

single component solution

temp. de almacenamiento

−20°C

cadena SMILES

CN1C(=O)N(C)c2ncn(C)c2C1=O

InChI

1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3

Clave InChI

RYYVLZVUVIJVGH-UHFFFAOYSA-N

Información sobre el gen

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Descripción general

This Snap-N-Spike® Reference Solution is suitable for use in LC/MS or GC/MS applications from clinical toxicology to dietary supplement testing.

Caffeine belongs to the class of active alkaloid compounds, mainly found in the leaves, fruits, and seeds of about 63 plant species. Coffee beans are the primary source of caffeine, in addition to tea leaves, chocolates, and energy drinks soft drinks. It is a central nervous system stimulant and acts by increasing alertness and reducing sleep.

Aplicación

The Certified Reference Material (CRM) in solution can also be used as follows:
  • To determine caffeine content in an aqueous solution of green coffee beans by two methods based on Fourier transform infrared spectroscopy-attenuated total reflectance (FTIR-ATR) and fluorescence spectrophotometry
  • Extraction of caffeine by automated homogeneous liquid-liquid microextraction (A-HLLME) from five different beverage samples for its quantification by high-performance liquid chromatography combined with UV detection
  • Simultaneous estimation of caffeine and chlorogenic acids in ground green coffee samples by a UV/Vis spectrometric method
  • Multi-residue determination of caffeine and paracetamol by square-wave voltammetry using poly(4-amino-3-hydroxynaphthalene sulfonic acid)-modified glassy carbon electrode (poly(AHNSA)/GCE in coca-cola, pepsi, and tea samples
  • Cyclic voltammetric and differential pulse voltammetric based detection and quantitative analysis of paracetamol, tryptophan, and caffeine, both separately and simultaneously, using an electrochemical sensor founded on tin sulfide (SnS)-titanium dioxide (TiO2)-graphene oxide (GO) composite modified glassy carbon electrode

Características y beneficios

  • Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
  • Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
  • Rigorously tested through real-time stability studies to ensure accuracy and shelf life
  • Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
  • Flame sealed under argon into ampoules for long-term shelf life
  • Offered in a convenient, DEA-exempt format to improve laboratory efficiency

Información legal

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Código de clase de almacenamiento

3 - Flammable liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

49.5 °F - closed cup

Punto de inflamabilidad (°C)

9.7 °C - closed cup


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G A Wright et al.
Science (New York, N.Y.), 339(6124), 1202-1204 (2013-03-09)
Plant defense compounds occur in floral nectar, but their ecological role is not well understood. We provide evidence that plant compounds pharmacologically alter pollinator behavior by enhancing their memory of reward. Honeybees rewarded with caffeine, which occurs naturally in nectar
Maria Dobrinas et al.
Pharmacogenetics and genomics, 23(5), 286-292 (2013-03-16)
There is a high interindividual variability in cytochrome P4501A2 (CYP1A2) activity and in its inducibility by smoking, only poorly explained by known CYP1A2 polymorphisms. We aimed to study the contribution of other regulatory pathways, including transcription factors and nuclear receptors
France Denoeud et al.
Science (New York, N.Y.), 345(6201), 1181-1184 (2014-09-06)
Coffee is a valuable beverage crop due to its characteristic flavor, aroma, and the stimulating effects of caffeine. We generated a high-quality draft genome of the species Coffea canephora, which displays a conserved chromosomal gene order among asterid angiosperms. Although
Pierre Ayotte et al.
Environmental health perspectives, 113(10), 1318-1324 (2005-10-06)
The Lower North Shore region of the St. Lawrence River is home to a fish-eating population that displays an unusually high body burden of several organochlorines, including polychlorinated biphenyls (PCBs) and dioxin-like compounds (DLCs). We measured biomarkers indicative of liver
Jack E James
Psychosomatic medicine, 66(1), 63-71 (2004-01-30)
This review aims to determine whether, and to what extent, dietary caffeine may be a risk to cardiovascular health. A critical review of the relevant experimental and epidemiologic literature was conducted, with particular reference to studies of caffeine and blood

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