C-007

Codeine-D₃ solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Fórmula empírica (notación de Hill): C₁₈H₁₈D₃NO₃
• Número de CAS: 70420-71-2
• Peso molecular: 302.38
• Número CE: 200-659-6
• Número MDL: MFCD01075373
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329774760
• NACRES: NA.24

Propiedades

• grado: certified reference material
• Nivel de calidad: 300
• Formulario: liquid
• Características: SNAP-N-SPIKE^®, SNAP-N-SHOOT^®
• envase: ampule of 1 mL
• fabricante / nombre comercial: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• concentración: 1.0 mg/mL in methanol
• técnicas: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• aplicaciones: forensics and toxicology
• Formato: single component solution
• temp. de almacenamiento: −20°C
• cadena SMILES: [2H]C([2H])([2H])N1CC[C@]23[C@H]4Oc5c(OC)ccc(C[C@@H]1[C@@H]2C=C[C@@H]4O)c35
• InChI: 1S/C18H21NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3-6,11-13,17,20H,7-9H2,1-2H3/t11-,12+,13-,17-,18-/m0/s1/i1D3
• Clave InChI: OROGSEYTTFOCAN-SBGSAQJDSA-N

Descripción

Descripción general

Codeine-D₃ is a stable-labeled internal standard suitable for many LC/MS or GC/MS testing applications including pain prescription monitoring, forensic analysis, clinical toxicology, urine drug testing or isotope dilution methods. Codeine is an opiate used for its analgesic, antitussive, and sedative properties and is the second-most predominant alkaloid in opium. Since opiate drugs are classified as controlled substances, Cerilliant offers most opiate reference standards as DEA-exempt solutions for added convenience.

Aplicación

<ul>
<li><strong>Codeine-D3 analytical standard in opioid detection:</strong> Codeine-D3 is used as an internal standard for the accurate determination of opioids in blood and pericardial fluid, enhancing forensic and clinical toxicology analyses (Ferreira et al., 2020).</li>
<li><strong>Deuterated codeine for research in plasma opioid quantification:</strong> Comparison of mass spectrometry techniques using Codeine-D3 to quantify opioids in human plasma highlights its application in enhancing the sensitivity and specificity of pharmacokinetic studies (Viaene et al., 2016).</li>
<li><strong>Codeine isotopic label in urinary opiate analysis:</strong> An LC-MS method was validated using Codeine-D3, proving its efficacy in the accurate determination of urinary opiate metabolites, thereby supporting drug monitoring and compliance testing (Svensson et al., 2007).</li>
<li><strong>High-purity Codeine-D3 for biochemistry research:</strong> Codeine-D3 was crucial in validating a direct injection electrospray LC-MS/MS technique for opiates in urine drug testing, underscoring its utility in clinical diagnostics and forensic investigations (Gustavsson et al., 2007).</li>
</ul>

Información legal

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Pictogramas: GHS02,GHS06,GHS08
• Palabra de señalización: Danger
• Frases de peligro: H225,H301 + H311 + H331,H370
• Consejos de prudencia: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Clasificaciones de peligro: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Órganos de actuación: Eyes,Central nervous system
• Código de clase de almacenamiento: 3 - Flammable liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): 49.5 °F - closed cup
• Punto de inflamabilidad (°C): 9.7 °C - closed cup