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Key Documents

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A45807

Sigma-Aldrich

2-Amino-5-chlorobenzoxazole

97%

Sinónimos:

Zoxazolamine

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About This Item

Fórmula empírica (notación de Hill):
C7H5ClN2O
Número de CAS:
61-80-3
Peso molecular:
168.58
EC Number:
200-519-4
MDL number:
MFCD00005770
UNSPSC Code:
12352100
PubChem Substance ID:
24890884
NACRES:
NA.22

assay

97%

form

powder

mp

181-184 °C (lit.)

SMILES string

Nc1nc2cc(Cl)ccc2o1

InChI

1S/C7H5ClN2O/c8-4-1-2-6-5(3-4)10-7(9)11-6/h1-3H,(H2,9,10)

InChI key

YGCODSQDUUUKIV-UHFFFAOYSA-N

Pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Huidi Jiang et al.
Die Pharmazie, 58(9), 654-656 (2003-10-09)
The present paper aims to investigate whether p-amino-2',4'-dichlorodiphenyl ether and p-amino-4'-methyldiphenyl ether are inhibitors as well as inducers of P450. Mice were given daily intraperitoneal (ip) injections of p-amino-2',4'-dichlorodiphenyl ether (0.25 mmol/kg) or p-amino-4'-methyldiphenyl ether (0.25 mmol/kg) for 4 days
Romi Ghose et al.
Life sciences, 89(1-2), 57-64 (2011-05-31)
Our aim is to investigate the molecular mechanism of regulation of gene expression of drug metabolizing enzymes (DMEs) and transporters in diet-induced obesity. Adult male CD1 mice were fed diets containing 60% kcal fat (HFD) or 10% kcal fat (LFD)
Yuzhi Jia et al.
Proceedings of the National Academy of Sciences of the United States of America, 102(35), 12531-12536 (2005-08-20)
Peroxisome proliferator-activated receptor-binding protein (PBP), also known as thyroid hormone receptor-associated protein 220/vitamin D receptor-interacting protein 205/mediator 1, an anchor for multisubunit mediator transcription complex, functions as a transcription coactivator for nuclear receptors. Disruption of the PBP gene results in
W Tracewell et al.
Toxicology and applied pharmacology, 135(2), 179-184 (1995-12-01)
CYP1A1 gene expression is regulated by known cis- and transacting elements controlling inhibition and induction of CYP1A1 transcription. The influence of a double-stranded phosphorothioate oligonucleotide (dsODN) with sequence identical to the CYP1A1 negative regulatory element (NRE) was examined in Sprague-Dawley
Juan P Hernandez et al.
Toxicology and applied pharmacology, 216(2), 186-196 (2006-07-11)
Nonylphenol (NP) is a breakdown product of nonylphenol ethoxylates, which are used in a variety of industrial, agricultural, household cleaning, and beauty products. NP is one of the most commonly found toxicants in the United States and Europe and is
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