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900614

Sigma-Aldrich

3-(4-(Prop-2-yn-1-yloxy)benzoyl)benzoic acid

≥95%

Sinónimos:

Carboxyl benzophenone alkyne, Probe building block

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About This Item

Fórmula empírica (notación de Hill):
C17H12O4
Número de CAS:
2140866-80-2
Peso molecular:
280.27
UNSPSC Code:
12352106
NACRES:
NA.22

Quality Level

100

assay

≥95%

form

solid

reaction suitability

reaction type: click chemistry

storage temp.

−20°C

Application

3-(4-(Prop-2-yn-1-yloxy)benzoyl)benzoic acid is used for chemical probe synthesis, this trifunctional building block contains a light-activated benzophenone, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Other Notes


Technology Spotlight: Trifuctional Probe Building Blocks

A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS

related product

Referencia del producto
Descripción
Precios

900603

(4-(2-(2-Aminoethoxy)ethoxy)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone, ≥95%

900598

(4-(Bromomethyl)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone, ≥95%

900599

(4-(Aminomethyl)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone, 95%

900600

3-(Fluorosulfonyl)-5-((trimethylsilyl)ethynyl)benzoic acid, ≥95%

900601

3-Formyl-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride, ≥95%

900602

4-(4-(Prop-2-yn-1-yloxy)benzoyl)benzoic acid, ≥95%

900605

3-(Bromomethyl)-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride, ≥95%

900615

(4-Hydroxyphenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone, ≥95%

900613

5-(4-(4-(Prop-2-yn-1-yloxy)benzoyl)phenoxy)pentanoic acid, ≥95%

900611

(3-Hydroxyphenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone, ≥95%

900610

Hydroxyl di-benzophenone (PEG)3 alkyne

900617

(4-(Hydroxymethyl)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone, ≥95%

900619

4-(4-(Prop-2-yn-1-yloxy)benzoyl)benzaldehyde, ≥95%

900616

3-(But-3-yn-1-yl)-3-(2-iodoethyl)-3H-diazirine, ≥95%

900618

3-(3-(Bromomethyl)-5-ethynylphenyl)-3-(trifluoromethyl)-3H-diazirine, 95%

900683

2-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)ethan-1-amine, 95%

900750

(4-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone HCl salt, ≥95%

900831

3-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)propanoic acid

900848

4-Amino-2-trimethylsilanylethynyl-benzenesulfonyl fluoride

900847

4-(Fluorosulfonyl)-3-((trimethylsilyl)ethynyl)benzoic acid, ≥95%

900858

2-(Prop-2-yn-1-yloxy)-4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzoic acid, ≥95%

900860

3-Amino-5-ethynylbenzenesulfonyl fluoride, ≥95%

900862

(4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)-2-((trimethylsilyl)ethynyl)phenyl)methanol

900859

3-Bromo-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride, ≥95%

900863

2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol, ≥95%

900864

4-(Bromomethyl)-2-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride, ≥95%

900865

4-Formyl-2-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride, ≥95%

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Artículos

Trifunctional Probe Building Blocks

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

Trifunctional Probe Building Blocks

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

Trifunctional Probe Building Blocks

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

Trifunctional Probe Building Blocks

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

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