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Key Documents

746614

Sigma-Aldrich

SAM Formation reagent for carboxylic acid terminated monolayer on gold surface

Sinónimos:

Carboxylic acid-SAM

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About This Item

UNSPSC Code:
12352103
NACRES:
NA.23

form

liquid

Quality Level

storage temp.

2-8°C

General description

Carboxylic acid- SAM is an acid terminated self-assembled monolayer on the surface of gold, which is mainly utilized to immobilize the surface atoms. The SAM film formed has a high degree of molecular orientation. This reagent is majorly utilized in surface science, biomineralization, and sensor based applications.

Application

Used to prepare carboxylic acid- terminated self-assembled monolayers (SAMs) on gold surfaces as biosensors detected by QCM (Quartz Crystal Microbalance), SPR (Surface Plasmon Resonance), and electrochemical analysis.
Coupled with carboxyl group activation method using NHS/WSC, carboxylic acid-SAM can be used as an interface to immobilize proteins or peptides and other ligands on gold surfaces.
This SAM Formation Reagent presents less non-specific binding than those commonly prepared with carboxylic acid-SAM.
Storage: Keep tightly closed; packed under Nitrogen gas; store in cooler (0~5 °C); dark and dry place.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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J Christopher Ball et al.
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Effects of self-assembled monolayers on amperometric glucose biosensors based on an organic-inorganic hybrid system
Wang, Huihui;
Sensors and Actuators B, Chemical, 168, 249-255 (2012)
Influence of gold substrate topography on the voltammetry of cytochrome c adsorbed on carboxylic acid terminated self-assembled monolayers.
Leopold MC and Bowden EF
Langmuir, 18(6), 2239-2245 (2002)
Preparation, modification, and crystallinity of aliphatic and aromatic carboxylic acid terminated self-assembled monolayers.
Arnold R, et al.
Langmuir, 18(10), 3980-3992 (2002)

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