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388920

Sigma-Aldrich

Sorbitan monopalmitate

Sinónimos:

Span® 40

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About This Item

Fórmula empírica (notación de Hill):
C22H42O6
Número de CAS:
26266-57-9
Peso molecular:
402.57
EC Number:
247-568-8
MDL number:
MFCD00080946
UNSPSC Code:
12162002
PubChem Substance ID:
24864252
NACRES:
NA.23

form

solid

mp

46-47 °C (lit.)

HLB

6

SMILES string

CCCCCCCCCCCCCCCC(=O)OC[C@H](O)[C@H]1OC[C@H](O)[C@H]1O

InChI

1S/C22H42O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-20(25)27-17-19(24)22-21(26)18(23)16-28-22/h18-19,21-24,26H,2-17H2,1H3/t18-,19?,21+,22+/m0/s1

InChI key

IYFATESGLOUGBX-NDUCAMMLSA-N

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Legal Information

Span is a registered trademark of Croda International PLC

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Drug development and industrial pharmacy, 43(9), 1450-1459 (2017-04-20)
Dermal drug delivery system which localizes methotrexate (MTX) in the skin is advantageous in topical treatment of psoriasis. The aim of the current study was to understand dilution effects and formulation variability for the potential formation of niosomes from proniosome
Farid Badria et al.
Drug design, development and therapy, 14, 3697-3721 (2020-09-29)
The current study aimed to discuss the potential of nanospanlastics as a surfactant-based vesicular system for improving the topical delivery of 3-acetyl-11-keto-β-boswellic acid (AKBA). AKBA is a potent anti-inflammatory drug, but it has poor oral bioavailability due to its poor
Kamal K Upadhyay et al.
Drug development and industrial pharmacy, 33(6), 617-625 (2007-07-07)
The partial phase behavior, rheological, and drug release characteristics of an organogel (OG) composed of water, isooctane and sorbitan esters, sorbitan monopalmitate (Span-40) and poly(oxyethylene)sorbitan monostearate (Polysorbate-60) were studied. Phase diagrams showed decreasing areas of optically isotropic organogel region depending
S C Chattaraj et al.
Drug delivery, 10(2), 73-77 (2003-05-15)
The goal of this study was to develop nonionic surfactant vesicles of influenza antigen for nasal mucosal delivery. The study describes the encapsulation of viral influenza vaccine antigen in nonionic surfactant vesicles using dehydration-rehydration technique and investigation of the influence
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Journal of microencapsulation, 34(3), 250-261 (2017-05-31)
The aim of this study was to develop docetaxel-incorporated lipid nanoparticles (DTX-NPs) to improve the pharmacokinetic behaviour of docetaxel (DTX) after oral and parenteral administration via sustained release. DTX-NPs were prepared by nanotemplate engineering technique with palmityl alcohol as a
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