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126462

Sigma-Aldrich

6,7-Dimethyl-2,3-di(2-pyridyl)quinoxaline

98%

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About This Item

Fórmula empírica (notación de Hill):
C20H16N4
Número de CAS:
6627-38-9
Peso molecular:
312.37
EC Number:
229-592-0
MDL number:
MFCD00006730
UNSPSC Code:
12352100
PubChem Substance ID:
24847727
NACRES:
NA.22

assay

98%

form

powder

mp

191-193 °C (lit.)

SMILES string

Cc1cc2nc(-c3ccccn3)c(nc2cc1C)-c4ccccn4

InChI

1S/C20H16N4/c1-13-11-17-18(12-14(13)2)24-20(16-8-4-6-10-22-16)19(23-17)15-7-3-5-9-21-15/h3-12H,1-2H3

InChI key

NACXMBPTPBZQHY-UHFFFAOYSA-N

Categorías relacionadas

Application

6,7-Dimethyl-2,3-di-(2-pyridyl)quinoxaline has been used as an internal standard to investigate the clinical pharmacokinetics of nelfinavir mesylate, a potent inhibitor of HIV-1 protease.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Journal of chromatography. B, Biomedical sciences and applications, 695(2), 373-380 (1997-08-01)
Nelfinavir mesylate, a potent and orally bioavailable inhibitor of HIV-1 protease (Ki=2 nM), has undergone Phase III clinical evaluation in a large population of HIV-positive patients. A high-performance liquid chromatography analytical method was developed to determine the pharmacokinetic parameters of
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