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D2004

Sigma-Aldrich

4-(Dimethylamino)benzaldehyde

suitable for histochemical demonstration of nitro blue tetrazolium reduction in neutrophils

Synonym(s):

p-Dimethylaminobenzaldehyde, DMAB, Ehrlich’s reagent

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About This Item

Linear Formula:
(CH3)2NC6H4CHO
CAS Number:
100-10-7
Molecular Weight:
149.19
Beilstein:
606802
EC Number:
202-819-0
MDL number:
MFCD00003381
UNSPSC Code:
12171500
PubChem Substance ID:
57654078
NACRES:
NA.47

Assay

≥99% (TLC)

Quality Level

200

form

powder

mp

72-75 °C (lit.)

solubility

ethanol: 50 mg/mL

suitability

suitable for histochemical demonstration of nitro blue tetrazolium reduction in neutrophils

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

CN(C)c1ccc(C=O)cc1

InChI

1S/C9H11NO/c1-10(2)9-5-3-8(7-11)4-6-9/h3-7H,1-2H3

InChI key

BGNGWHSBYQYVRX-UHFFFAOYSA-N

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Application

4-(Dimethylamino)benzaldehyde (DMAB or Ehrlich’s reagent) has been used as a color reagent for the determination of hydroxyproline level.It forms colored condensation products (Schiff bases) with pyrroles and primary amines. DMAB is also suitable as a reagent to develop latent fingermarks on paper surfaces yielding impressions that are both colored and photoluminescent.
Forms colored condensation products (Schiff bases) with pyrroles and primary amines.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H317

Hazard Classifications

Skin Sens. 1B

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

327.2 °F - closed cup

Flash Point(C)

164 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Jamie Morrison et al.
The American journal of pathology, 166(6), 1701-1710 (2005-05-28)
Duchenne muscular dystrophy was initially described as a myosclerosis because of the conspicuous progression of interstitial fibrosis. Using the mdx mouse homologue, we have shown previously that the accumulation of intramuscular collagen is profoundly influenced by the presence or absence
M Stefek et al.
Biochimica et biophysica acta, 1502(3), 398-404 (2000-11-09)
In the present work, pepsin digests of tail tendons from streptozotocin-diabetic rats were found to contain material that reacted rapidly at room temperature with p-dimethylaminobenzaldehyde (Ehrlich's reagent) to give an adduct with an absorbance spectrum characteristic of the Ehrlich chromogen
Rosario Zamora et al.
Journal of agricultural and food chemistry, 52(13), 4166-4171 (2004-06-24)
The Ehrlich reaction was optimized to determine the formation of pyrrolized phospholipids in edible oils in an attempt to understand the color reversion produced during the deodorization of poorly degummed edible oils. The procedure consisted of the treatment of the
C Creuzenet et al.
The Journal of biological chemistry, 275(45), 34873-34880 (2000-08-24)
FlaA1 is a small soluble protein of unknown function in Helicobacter pylori. It has homologues that are essential for the virulence of numerous medically relevant bacteria. FlaA1 was overexpressed as a histidine-tagged protein and purified to homogeneity by nickel chelation
J D Brady et al.
The Journal of biological chemistry, 276(22), 18812-18818 (2001-03-30)
The structures of pyrrolic forms of cross-links in collagen have been confirmed by reacting collagen peptides with a biotinylated Ehrlich's reagent. This reagent was synthesized by converting the cyano group of N-methyl-N-cyanoethyl-4-aminobenzaldehyde to a carboxylic acid, followed by conjugation with
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