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C8784

Sigma-Aldrich

Anti-Corticosterone antibody produced in rabbit

whole antiserum, lyophilized powder

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About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

whole antiserum

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

technique(s)

radioimmunoassay: suitable (dextran coated charcoal 3H RIA)

storage temp.

2-8°C

target post-translational modification

unmodified

General description

Corticosterone is a steroid hormone produced mainly in the cortex of adrenal glands. It also known as the stress hormone and has a crucial role in enhancing and suppressing synaptic plasticity and memory processes.Rabbit anti-corticosterone antibody reacts specifically with corticosterone.

Immunogen

Corticosterone-21-Thyroglobulin

Application

Anti-corticosterone antibody can be used to measure total CORT level in serum using radioimmunoassay.

Physical form

The product is provided as a pre-diluted antiserum that has been lyophilized. Each vial contains no more than 20 mg Polyvinylpyrrolidone (PVP).

Reconstitution

Reconstitute with 5 mL buffer: 0.05 M Tris-HCl, pH 8.0, 0.1 M sodium chloride, 0.1% bovine serum albumin, and 0.1% sodium azide. Store this stock at −20 °C. Working dilution (1:10) to be discarded if unused within 12 hours.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Stéphane Martin et al.
PloS one, 4(3), e4714-e4714 (2009-03-24)
The stress hormone corticosterone has the ability both to enhance and suppress synaptic plasticity and learning and memory processes. However, until today there is very little known about the molecular mechanism that underlies the bidirectional effects of stress and corticosteroid
Daniel A Warner et al.
Proceedings. Biological sciences, 274(1611), 883-890 (2007-01-26)
Life-history traits such as offspring size, number and sex ratio are affected by maternal feeding rates in many kinds of animals, but the consequences of variation in maternal diet quality (rather than quantity) are poorly understood. We manipulated dietary quality
Sabrina G V Dutra et al.
Neuroendocrinology, 111(1-2), 70-86 (2020-01-20)
Furosemide is a loop diuretic widely used in clinical practice for the treatment of oedema and hypertension. The aim of this study was to determine physiological and molecular changes in the hypothalamic-neurohypophysial system as a consequence of furosemide-induced sodium depletion.
Heidi M Tate et al.
Conservation physiology, 9(1), coab090-coab090 (2021-12-04)
'The Blob', a mass of anomalously warm water in the Northeast Pacific Ocean peaking from 2014 to 2016, caused a decrease in primary productivity with cascading effects on the marine ecosystem. Among the more obvious manifestations of the event were
Glenn T Crossin et al.
General and comparative endocrinology, 193, 112-120 (2013-07-31)
Life-history theory predicts that costs are associated with reproduction. One possible mediator of costs involves the secretion of glucocorticoid hormones, which in birds can be measured in feathers grown during the breeding period. Glucocorticoids mediate physiological responses to unpredictable environmental

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