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P33429

Sigma-Aldrich

4-Phenylpyridine

97%

Synonym(s):

γ-Phenylpyridine, 1-Benzylhydrazine dihydrochloride, p-Phenylpyridine

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About This Item

Empirical Formula (Hill Notation):
C11H9N
CAS Number:
939-23-1
Molecular Weight:
155.20
Beilstein:
110490
EC Number:
213-357-4
MDL number:
MFCD00006420
UNSPSC Code:
12352100
PubChem Substance ID:
24898403
NACRES:
NA.22

Quality Level

100

Assay

97%

form

crystals

bp

274-275 °C (lit.)

mp

69-73 °C (lit.)

SMILES string

c1ccc(cc1)-c2ccncc2

InChI

1S/C11H9N/c1-2-4-10(5-3-1)11-6-8-12-9-7-11/h1-9H

InChI key

JVZRCNQLWOELDU-UHFFFAOYSA-N

Gene Information

human ... MMP3(4314)

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Related Categories

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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L A Carr et al.
European journal of pharmacology, 215(2-3), 285-287 (1992-05-14)
To determine whether the attenuation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity by tobacco smoke exposure is caused by inhibition of the neuronal uptake of 4-phenylpyridinium ion (MPP+), various tobacco components and a smoke extract were tested for inhibitory activity in striatal synaptosomes.
Camilla C Golfeto et al.
Journal of inorganic biochemistry, 104(5), 489-495 (2010-02-02)
The synthesis and characterization of ruthenium compounds of the type [RuCl(2)(NO)(dppp)(L)]PF(6) [dppp=1,3-bis(diphenylphosphino)propane; L=pyridine, 4-methylpyridine, 4-phenylpyridine and dimethyl sulfoxide] are described. The complexes were characterized by elemental analysis, UV/Vis and infrared spectroscopy, cyclic voltammetry, and X-ray crystallography for the complexes with
M R Gluck et al.
The Journal of biological chemistry, 269(5), 3167-3174 (1994-02-04)
We have investigated the mechanism of the inhibition of membrane-bound NADH dehydrogenase by 1-methyl-4-phenylpyridinium (MPP+) and a series of its 4'-alkyl-substituted analogs of increasing hydrophobicity, as well as their neutral, desmethyl congeners. Comparison of hydrophobicity, as measured by partition coefficients
C C Huang et al.
Brain research, 753(1), 27-35 (1997-04-04)
The effects of L-deprenyl (selegiline), a highly selective monoamine oxidase type B (MAO-B) inhibitor, on cell excitability of rat hippocampal CA1 neurons were examined in slice preparations using intracellular recording techniques. Superfusion of L-deprenyl (10 and 20 microM) reversibly limited
L A Carr et al.
Life sciences, 48(12), 1173-1177 (1991-01-01)
Exposure to cigarette smoke has been found to attenuate the reduction in striatal dopamine levels caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in mice and to inhibit monoamine oxidase (MAO) activity in brain tissue. To confirm whether specific smoke constituents which have been
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