13454

N-Benzylhydroxylamine hydrochloride

puriss., ≥99.0% (AT)

• Linear Formula: C₆H₅CH₂NHOH · HCl
• CAS Number: 29601-98-7
• Molecular Weight: 159.61
• Beilstein: 507948
• MDL number: MFCD00043377
• UNSPSC Code: 12352100
• PubChem Substance ID: 57647092
• NACRES: NA.22

Properties

• grade: puriss.
• Quality Level: 100
• Assay: ≥99.0% (AT)
• form: solid
• mp: ~105 °C; 108-110 °C (lit.)
• SMILES string: Cl.ONCc1ccccc1
• InChI: 1S/C7H9NO.ClH/c9-8-6-7-4-2-1-3-5-7;/h1-5,8-9H,6H2;1H
• InChI key: YSNXOQGDHGUKCZ-UHFFFAOYSA-N

Description

Application

N-Benzylhydroxylamine hydrochloride was used in the synthesis of sugar derived nitrones. It was used as starting reagent in the synthesis of fluoro isoxazoline and isoxazolidine derivatives using flouro nitrone.

Biochem/physiol Actions

N-Benzylhydroxylamine is a potential pharmacological agent in the prevention and progression of acrolein-induced damage to the retinal pigment epithelium.

Other Notes

Formation of nitrones from carbonyl compounds and [2+3]-cycloaddition with olefins to isoxazolidines, which are versatile intermediates; Pd-catalyzed hydroxylamination of allylic esters.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves