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Interleukin-1RA Mitigates SARS-CoV-2-Induced Inflammatory Lung Vascular Leakage and Mortality in Humanized K18-hACE-2 Mice.

Arteriosclerosis, thrombosis, and vascular biology (2021-09-10)
Shiqin Xiong, Lianghui Zhang, Justin M Richner, Jake Class, Jalees Rehman, Asrar B Malik
RESUMEN

[Figure: see text].

MATERIALES
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Sigma-Aldrich
Cóctel de inhibidores de proteasas, for use with mammalian cell and tissue extracts, DMSO solution
Sigma-Aldrich
Seroalbúmina bovina, heat shock fraction, pH 7, ≥98%
Sigma-Aldrich
IL-1R Antagonist, The IL-1R Antagonist, also referenced under CAS 566914-00-9, controls the biological activity of IL-1R.