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Merck

1659000

USP

Timerosal

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

Etilmercuritiosalicilato de sodio, Mercuri-([o-carboxifenil]tio)etil sodium salt, Ácido 2-(etilmercuriomercapto)benzoico sodium salt, Ácido etilmercuritiosalicílico sodium salt

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About This Item

Fórmula lineal:
2-(C2H5HgS)C6H4CO2Na
Número de CAS:
Peso molecular:
404.81
Beilstein/REAXYS Number:
8169555
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

thimerosal

manufacturer/tradename

USP

mp

234-237 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[Na+].CC[Hg]Sc1ccccc1C([O-])=O

InChI

1S/C7H6O2S.C2H5.Hg.Na/c8-7(9)5-3-1-2-4-6(5)10;1-2;;/h1-4,10H,(H,8,9);1H2,2H3;;/q;;2*+1/p-2

InChI key

RTKIYNMVFMVABJ-UHFFFAOYSA-L

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Thimerosal USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Thimerosal Tincture
  • Thimerosal Topical Aerosol®
  • Thimerosal Topical Solution

Biochem/physiol Actions

El timerosal es un reactivo oxidante de sulfhidrilo (tiol) capaz de inhibir una amplia variedad de enzimas dependientes del sulfhidrilo y proteínas como la metionina sintasa dependiente de PI3-cinasa, receptores de transporte de glutamato y las ATPasas dependientes de Na++K+.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Legal Information

Aerosol is a registered trademark of Cytec Technology Corp.

Disclaimer

As part of the corporationglobal plan to support the Minamata Convention in eliminatingmercury-containing compounds, as of January 2021 customers will be required toprovide an End-Use Declaration. The sales of thimerosal will be restricted forapproved applications only, such as preservative in vaccine manufacturing,preservative in eye cosmetics, research use within academia (excludingpreservation intent) and as reference material only. The product is notintended for use as a biocide under global biocide regulations, including butnot limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act ,European Biocidal Products Regulation, Canada’s Pest Management RegulatoryAgency, Turkey’s Biocidal Products Regulation,Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR)and others.

signalword

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2 Oral

target_organs

Kidney

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Los clientes también vieron

Thimerosal Topical Aerosol
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 4346-4346 (2018)
Thimerosal Topical Solution
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 4347-4347 (2013)
Thimerosal
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 40(5), 4344-4344 (2020)
Thimerosal Tincture
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 4348-4348 (2013)
Xiaoling Li et al.
Toxicological sciences : an official journal of the Society of Toxicology, 139(2), 452-465 (2014-03-29)
Thimerosal is a vaccine antimicrobial preservative which has long been suspected an iatrogenic factor possibly contributing to neurodevelopmental disorders including autism. The association between infant vaccine thimerosal exposure and autism remains an open question. Although thimerosal has been removed from

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