SML2789

tBPC

≥98% (HPLC)

• Sinónimos: 2-[4-(1,1-Dimethylethyl)phenoxy]cyclohexanol
• Fórmula empírica (notación de Hill): C₁₆H₂₄O₂
• Número de CAS: 1942-71-8
• Peso molecular: 248.36
• Número MDL: MFCD00155433
• Código UNSPSC: 12352200
• NACRES: NA.77

Propiedades

• Nivel de calidad: 100
• Ensayo: ≥98% (HPLC)
• Formulario: powder
• color: white to beige
• solubilidad: DMSO: 2 mg/mL, clear
• temp. de almacenamiento: 2-8°C
• cadena SMILES: O(C2C(CCCC2)O)c1ccc(cc1)C(C)(C)C
• InChI: 1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3
• Clave InChI: FTIXUILRMBSXNS-UHFFFAOYSA-N

Descripción

Acciones bioquímicas o fisiológicas

Postitive allosteric modulator of NPY Y4 receptor

tBPC is a postitive allosteric modulator of the neuropeptide Y (NPY) Y4 receptor, which is predominantly expressed in the gastrointestinal tract and activated most strongly by pancreatic polypeptide (PP). tBPC was shown to potentiate Y4R activity in G-Protein signaling and arrestin3 recruitment and to potentiate the native PP response. tBPC was selective for Y4R over other Neuropeptide Y receptors and showed no effect on the efficacy (E_max) or potency (EC₅₀) of the NPY signal response at the Y1, Y2, or Y5 receptors at 30 μM.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3