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SML0437

Sigma-Aldrich

Oxandrolone

≥98% (HPLC)

Sinónimos:

17β-Hydroxy-17α-methyl-2-oxa-5α-androstan-3-one, 8075CB, NSC 67068, Oxandren, Provitar, SC 11585, Vasorome

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About This Item

Fórmula empírica (notación de Hill):
C19H30O3
Número de CAS:
53-39-4
Peso molecular:
306.44
Número CE:
200-172-9
Número MDL:
MFCD00198944
Código UNSPSC:
51111800
ID de la sustancia en PubChem:
329824720
NACRES:
NA.77

Ensayo

≥98% (HPLC)

Formulario

powder

actividad óptica

[α]/D -19 to -26°, c = 1 (CDCl3)

control farmacológico

USDEA Schedule IIIN; regulated under CDSA - not available from Sigma-Aldrich Canada

color

white to beige

solubilidad

DMSO: 2 mg/mL (clear solution; warmed)

temp. de almacenamiento

2-8°C

cadena SMILES

C[C@]1(O)CC[C@H]2[C@@H]3CC[C@H]4CC(=O)OC[C@]4(C)[C@H]3CC[C@]12C

InChI

1S/C19H30O3/c1-17-11-22-16(20)10-12(17)4-5-13-14(17)6-8-18(2)15(13)7-9-19(18,3)21/h12-15,21H,4-11H2,1-3H3/t12-,13+,14-,15-,17-,18-,19-/m0/s1

Clave InChI

QSLJIVKCVHQPLV-PEMPUTJUSA-N

Información sobre el gen

human ... AR(367)

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Acciones bioquímicas o fisiológicas

Oxandrolone is a synthetic anabolic steroid. It is is a non-aromatizable androgen with no estrogenic effects and with mild androgenic activity. Clinical uses of oxandrolone include to promote weight gain after weight loss following extensive surgery or chronic infections or trauma, to offset the protein catabolism associated with prolonged administration of corticosteroids, to relieve bone pain frequently accompanying osteoporosis, and to treat Turner′s syndrome in girls.
Oxandrolone is an anabolic steroid.

Características y beneficios

This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Pictogramas

Health hazard
GHS08

Palabra de señalización

Danger

Frases de peligro

H351,H360FD

Clasificaciones de peligro

Carc. 2 - Repr. 1B

Código de clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
SLBJ0457V
035M4743V
082M4703V

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Rhonda Orr et al.
Drugs, 64(7), 725-750 (2004-03-18)
There has been increasing interest in the development of effective agents that can be safely used to promote anabolism in the clinical setting for patients with chronic wasting conditions as well as in the prevention and treatment of frailty associated
Yesenia Rojas et al.
Expert opinion on pharmacotherapy, 13(17), 2485-2494 (2012-11-06)
The worldwide occurrence of burn injuries remains high despite efforts to reduce injury incidence through public awareness campaigns and improvements in living conditions. In 2004, almost 11 million people experienced burns severe enough to warrant medical treatment. Advances over the
Leonie A Menke et al.
Journal of voice : official journal of the Voice Foundation, 25(5), 602-610 (2010-10-26)
Oxandrolone (Ox) increases height gain but may also cause voice deepening in growth hormone (GH)-treated girls with Turner syndrome (TS). We assessed the effect of Ox on objective and subjective speaking voice frequency in GH-treated girls with TS. A multicenter
Leonie A Menke et al.
Hormone research in paediatrics, 75(2), 115-122 (2010-09-04)
The weak androgen oxandrolone (Ox) may increase height but may also affect glucose metabolism in girls with Turner syndrome (TS). In a randomized, placebo-controlled, double-blind study, we assessed the effect of Ox at a dosage of either 0.06 or 0.03
Martha P D Zeger et al.
Hormone research in paediatrics, 75(1), 38-46 (2010-08-25)
Untreated girls with Turner syndrome (TS) have growth failure, and adult height is, on average, 20 cm less than predicted height. Treatment with growth hormone (GH) is now standard of care. The objective of this study was to investigate the
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