SAB5701803

Anti-Phospho-IRF3-S386 antibody produced in rabbit

• UNSPSC Code: 12352203
• NACRES: NA.41
• clone: polyclonal
• application: WB
• species reactivity: human
• technique(s): western blot: 1:500-1:2000

Propiedades

• biological source: rabbit
• Quality Level: 100
• antibody product type: primary antibodies
• clone: polyclonal
• form: liquid
• species reactivity: human
• concentration: 2.28 mg/mL
• technique(s): western blot: 1:500-1:2000
• UniProt accession no.: Q14653
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer386)
• Gene Information: human ... IRF3(3661)

Descripción

General description

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Immunogen

A synthetic phosphorylated peptide around S386 of human IRF3.

Physical form

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Información de seguridad

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable