SAB4500888

Anti-FGFR3 antibody produced in rabbit

affinity isolated antibody

• Sinónimos: CD333, CD333 antigen, FGFR-3, Fibroblast growth factor receptor 3, JTK4
• Número MDL: MFCD02096346
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: buffered aqueous solution
• mol peso: antigen 87 kDa
• reactividad de especies: rat, mouse, human
• concentración: ~1 mg/mL
• técnicas: ELISA: 1:10000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• Nº de acceso NCBI: P22607
• Nº de acceso UniProt: P22607
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... FGFR3(2261)

Descripción

Descripción general

Anti-FGFR3 Antibody detects endogenous levels of total FGFR3 protein.

FGFR3 (fibroblast growth factor receptor 3) belongs to the fibroblast growth factor receptor (Fgfr) family of proteins. It has 19 exons, an extracellular ligand binding domain, a transmembrane domain and an intracellular tyrosine kinase domain. It is located on human chromosome 4p16.3.

Inmunógeno

The antiserum was produced against synthesized peptide derived from human FGFR3.

Immunogen Range: 131-180

Aplicación

Anti-FGFR3 antibody has been used in immunohistochemistry.

Acciones bioquímicas o fisiológicas

Germline mutations in FGFR3 (fibroblast growth factor receptor 3) results in autosomal dominant skeletal dysplasias like achondroplasia (ACH), thanatophoric dysplasia (TD) and hypochrondroplasia (HCH). The gene also controls cellular activity.

Características y beneficios

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Forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): nwg
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable