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SAB3500340

Sigma-Aldrich

Anti-PTK7 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Sinónimos:

Anti-CCK-4, Anti-Colon carcinoma kinase-4, Anti-Protein tyrosine Kinase 7

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41
En este momento no podemos mostrarle ni los precios ni la disponibilidad

origen biológico

rabbit

Nivel de calidad

conjugado

unconjugated

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

Formulario

buffered aqueous solution

reactividad de especies

rat, mouse, human

técnicas

immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... PTK7(5754)

Descripción general

Protein tyrosine kinase-7 (PTK7) is a transmembrane receptor, that belongs to the receptor protein tyrosine kinase (RTKs) family. It has an extracellular immunoglobulin-like domain, a transmembrane domain and an inert tyrosine kinase-like domain. PTK7 is located on human chromosome 6p21.

Inmunógeno

PTK7 antibody was raised against a 18 amino acid peptide from near the carboxy terminus of human PTK7.

Aplicación

Anti-PTK7 antibody has been used in immunohistochemistry.

Acciones bioquímicas o fisiológicas

Protein tyrosine kinase-7 (PTK7) stimulates cell proliferation and invasion. It plays a vital role embryonic development and disease. PTK7 controls radioresistance with the help of nuclear factor-κ B in esophageal squamous cell carcinoma.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Ligadura / enlace

The action of this antibody can be blocked using blocking peptide SBP3500340.

Forma física

Supplied in PBS with 0.02% sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Visite la Librería de documentos

Ron Chen et al.
Cancer research, 74(10), 2892-2902 (2014-03-22)
Lung cancer remains the most common cause of cancer-related death worldwide and it continues to lack effective treatment. The increasingly large and diverse public databases of lung cancer gene expression constitute a rich source of candidate oncogenic drivers and therapeutic
PTK7 regulates radioresistance through nuclear factor-kappa B in esophageal squamous cell carcinoma.
Park M, et al.
Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine, 37(10), 14217-14224 (2016)
PTK7 overexpression in colorectal tumors: Clinicopathological correlation and prognosis relevance.
Tian X, et al.
Oncology Reports, 36(4), 1829-1836 (2016)
Xiuyun Tian et al.
Oncology reports, 36(4), 1829-1836 (2016-08-09)
Colorectal cancer (CRC) has one of the highest mortality rates in the worldwide and its incidence has been increasing in recent years. Protein tyrosine kinase-7 (PTK7) is an inactive member of receptor protein tyrosine kinase (RPTK)-like molecules, which is involved
Undetectable and Decreased Expression of KIAA1949 (Phostensin) Encoded on Chromosome 6p21.33 in Human Breast Cancers Revealed by Transcriptome Analysis
Su YA, et al.
Journal of Cancer, 1, 38-50 (2010)

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