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Merck

S5545

Sigma-Aldrich

Anti-Serotonin antibody produced in rabbit

whole antiserum

Sinónimos:

Anti-Serotonin, Rabbit Anti-Serotonin, Serotonin Detection Antibody

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About This Item

Número MDL:
Código UNSPSC:
12352203
NACRES:
NA.41
En este momento no podemos mostrarle ni los precios ni la disponibilidad

origen biológico

rabbit

Nivel de calidad

conjugado

unconjugated

forma del anticuerpo

whole antiserum

tipo de anticuerpo

primary antibodies

clon

polyclonal

contiene

15 mM sodium azide

reactividad de especies

rat, human

envase

antibody small pack of 25 μL

técnicas

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:8,000 using sections of normal human appendix or serotonin-containing carcinoid tumors
immunohistochemistry (frozen sections): 1:5,000 using perfusion-fixed (4% paraformaldehyde), frozen sections of rat brain.

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... HTR1A(3350)

Descripción general

Serotonin/5-HT (5-hydroxytryptamine) is a neurotransmitters present in the brain. Anti-Serotonin specifically stains enterochromaffin cells in formalin-fixed, paraffin-embedded sections of normal human appendix and serotonin-containing carcinoid tumors. In the central nervous system (CNS), the antiserum reacts with serotonin-containing fibers in perfusion-fixed, free-floating sections of rat brain.

Especificidad

The antibody reacts with serotonin-containing fibers in paraformaldehyde perfusion-fixed, frozen sections of rat brain. The product specifically stains enterochromaffin cells in formalin-fixed, paraffin embedded sections of normal human appendix and serotonin-containing carcinoid tumors.

Inmunógeno

Serotonin creatinine sulfate complex conjugated with formaldehyde to BSA.

Aplicación

Anti-Serotonin antibody has been used in immunocytochemistry.

Acciones bioquímicas o fisiológicas

Serotonin/5-HT, the midbrain raphe system controls mood, emotion, cognition and motor functions, circadian and neuroendocrine rhythms, like food intake, sleep and reproductive activity. It participates in natural reward-related physiology and behaviour, from feeding to sexual activity.

Forma física

Supplied as a liquid containing 15 mM sodium azide as preservative.

Almacenamiento y estabilidad

For continuous use, store at 2-8 °C for a maximum of one month. For extended storage freeze in working aliquots. Repeated freezing and thawing, or storage in "frost-free" freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Visite la Librería de documentos

Roles for serotonin in neuroembryogenesis.
Bernard H, et al.
Serotonin, 477-506 (1981)
Martin Fritsch et al.
Frontiers in zoology, 10(1), 35-35 (2013-06-20)
One of the most interesting riddles within crustaceans is the origin of Cladocera (water fleas). Cladocerans are morphologically diverse and in terms of size and body segmentation differ considerably from other branchiopod taxa (Anostraca, Notostraca, Laevicaudata, Spinicaudata and Cyclestherida). In
Allelic Variation of Human Serotonin Transporter Gene Expression
Armin H, et al.
Journal of Neurochemistry, 66(6), 2621-2624 (1996)
Characterization of efferent projections of chemosensitive neurons in the caudal parapyramidal area of the rat brain
Ribas-Salgueiro JL, et al.
Brain Research Bulletin, 66(3), 235-248 (2005)
A review of central 5-HT receptors and their function
Barnes NM, et al.
Neuropharmacology, 38(8), 1083-1152 (1999)

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