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Merck
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P5498

Sigma-Aldrich

Anti-Pro-NGF antibody produced in rabbit

affinity isolated antibody, lyophilized powder

Sinónimos:

Anti-Pro-Nerve Growth Factor

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About This Item

Número MDL:
MFCD07370460
Código UNSPSC:
51111800
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

200

conjugado

unconjugated

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

Formulario

lyophilized powder

reactividad de especies

mouse, rat, human

técnicas

immunohistochemistry: suitable
western blot: 1:200-1:500

Nº de acceso UniProt

P08138

Condiciones de envío

wet ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... NGFR(4804)
mouse ... Ngfr(18053)
rat ... Ngfr(24596)

Categorías relacionadas

Especificidad

Does not cross react with pro-BDNF, pro-NT-3, or mature NGF.

Inmunógeno

peptide corresponding to amino acid residues 84-104 of rat NGF (precursor). The sequence is identical in mouse and 16/21 residues identical in human.

Forma física

Lyophilized from phosphate buffered saline, pH 7.4, 1% BSA and <0.1% sodium azide

Nota de preparación

Reconstitute the lyophilized vial with 0.2 ml deionized water.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Pictogramas

Exclamation mark
GHS07

Palabra de señalización

Warning

Frases de peligro

H312,H412

Clasificaciones de peligro

Acute Tox. 4 Dermal - Aquatic Chronic 3

Código de clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
SLCH9273
SLCF9500
SLBW8951
SLBV7581
SLBV4304

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Fan Zhang et al.
Molecular neurobiology, 58(9), 4237-4250 (2021-05-10)
Maternal subclinical hypothyroidism (SCH) during pregnancy can adversely affect the neurodevelopment of the offspring. The balance of nerve growth factor (NGF)-related tropomyosin receptor kinase A/p75 neurotrophin receptor (TrkA/p75NTR) signaling in the hippocampus is important in brain development, and whether it
Sabah Shiri et al.
RSC advances, 9(67), 38912-38927 (2019-11-27)
Drug delivery systems have been of interest to researchers. The effects of synthesized nano-polymers as silibinin and silymarin extract drug delivery systems on olfactory ensheathing cells under normal and high-glucose conditions were studied. The structure of the nanopolymer was characterized
Elahe Karimi et al.
Drug design, development and therapy, 13, 2513-2532 (2019-08-24)
Nowadays, the drug delivery system is important in the treatment of diseases. A polymeric nanoparticle modified by oleic acid (NPMO) as a Thymol (Thy) drug release system was synthesized from Thymbra spicata and its neurotrophic and angiogenic effects on rat's
Li Duan et al.
PloS one, 8(9), e73768-e73768 (2013-09-17)
While aberrant activation of microglial cells was evidently involved in neuroinflammation and neurotoxicity in the neurodegenerative diseases such as Alzheimer's and Parkinson's disease, objective of study was to address if activated microglias deliver their effect by releasing pro-neurotrophins. By in
Yi Xia et al.
International journal of molecular sciences, 14(7), 14085-14104 (2013-07-25)
Growing evidence has shown that proNGF-p75NTR-sortilin signaling might be a crucial factor in neurodegeneration, but it remains unclear if it may function in nigral neurons under aging and disease. The purpose of this study is to examine and quantify proNGF

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