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Key Documents

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M0821

Sigma-Aldrich

Moexipril hydrochloride

powder, ≥98% (HPLC)

Sinónimos:

(3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic acid hydrochloride

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About This Item

Fórmula empírica (notación de Hill):
C27H35N2O7Cl
Número de CAS:
82586-52-5
Peso molecular:
535.03
MDL number:
MFCD00940481
UNSPSC Code:
12352200
PubChem Substance ID:
329817832
NACRES:
NA.77

assay

≥98% (HPLC)

form

powder

solubility

H2O: 32 mg/mL

originator

UCB Inc.

storage temp.

2-8°C

SMILES string

Cl.CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N2Cc3cc(OC)c(OC)cc3C[C@H]2C(O)=O

InChI

1S/C27H34N2O7.ClH/c1-5-36-27(33)21(12-11-18-9-7-6-8-10-18)28-17(2)25(30)29-16-20-15-24(35-4)23(34-3)14-19(20)13-22(29)26(31)32;/h6-10,14-15,17,21-22,28H,5,11-13,16H2,1-4H3,(H,31,32);1H/t17-,21-,22-;/m0./s1

InChI key

JXRAXHBVZQZSIC-JKVLGAQCSA-N

Gene Information

human ... ACE(1636)

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Biochem/physiol Actions

Moexipril is an ACE-Inhibitor; Antihypertensive; Unlike other ACE inhibitors, prolongs QT interval leading to torsades de pointes and cardiad arrhythmia;

Features and Benefits

This compound is featured on the Angiotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by UCB Inc.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

pictograms

Environment
GHS09

signalword

Warning

hcodes

H400

Hazard Classifications

Aquatic Acute 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Mila Volchek et al.
Human reproduction (Oxford, England), 25(10), 2455-2464 (2010-08-24)
The mammalian placenta plays a central role in maternal tolerance of the semi-allogeneic fetus and fluid balance between the maternal and fetal compartments. The lymphatics play a role in both these function. The aim of this study was to describe
Thomas S Jacques et al.
The EMBO journal, 29(1), 222-235 (2009-11-21)
It has been suggested that intrinsic brain tumours originate from a neural stem/progenitor cell population in the subventricular zone of the post-natal brain. However, the influence of the initial genetic mutation on the phenotype as well as the contribution of
K E Kristensen et al.
Clinical pharmacology and therapeutics, 96(6), 713-722 (2014-09-16)
Clopidogrel is an oral antiplatelet prodrug, the majority of which is hydrolyzed to an inactive metabolite by hepatic carboxylesterase 1 (CES1). Most angiotensin-converting enzyme inhibitors (ACEIs) are also metabolized by this enzyme. We examined the effects of ACEIs on clopidogrel

Artículos

Angiotensin Receptors

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Angiotensin Receptors

We offer many products related to angiotensin receptors for your research needs.

Angiotensin Receptors

We offer many products related to angiotensin receptors for your research needs.

Angiotensin Receptors

We offer many products related to angiotensin receptors for your research needs.

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