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L9026

Sigma-Aldrich

Lys-Lys-Lys-Lys

≥95% (TLC)

Sinónimos:

Lys4, Tetralysine

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About This Item

Fórmula empírica (notación de Hill):
C24H50N8O5
Número de CAS:
997-20-6
Peso molecular:
530.70
MDL number:
MFCD00171343
UNSPSC Code:
12352209
PubChem Substance ID:
24896514
NACRES:
NA.26

product name

Lys-Lys-Lys-Lys, ≥95% (TLC)

assay

≥95% (TLC)

form

powder or crystals

composition

Peptide content, ≥50%

color

white

storage temp.

−20°C

SMILES string

NCCCCC(N)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(O)=O

InChI

1S/C24H50N8O5/c25-13-5-1-9-17(29)21(33)30-18(10-2-6-14-26)22(34)31-19(11-3-7-15-27)23(35)32-20(24(36)37)12-4-8-16-28/h17-20H,1-16,25-29H2,(H,30,33)(H,31,34)(H,32,35)(H,36,37)

InChI key

RRBGTUQJDFBWNN-UHFFFAOYSA-N

Amino Acid Sequence

Lys-Lys-Lys-Lys

Biochem/physiol Actions

Short poly-L-lysines polypeptides such as trilysine (lys3), tetralysine (tetra-L-lysine, lys4) and pentalysine (penta-L-lysine, lys5) are cationic moieties that may be used in the construction of gene delivery vectors and DNA nanoparticles.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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The transcription factor GATA-1-interacting protein Friend of GATA-1 (FOG1) is essential for proper transcriptional activation and repression of GATA-1 target genes; yet, the mechanisms by which FOG1 exerts its activating and repressing functions remain unknown. Forced FOG1 expression in human
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Science signaling, 11(547) (2018-09-13)
The bacterial serine-threonine protein kinase HipA promotes multidrug tolerance by phosphorylating the glutamate-tRNA ligase (GltX), leading to a halt in translation, inhibition of growth, and induction of a physiologically dormant state (persistence). The HipA variant HipA7 substantially increases persistence despite
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