E8909
Phosphodiesterase 3B
recombinant, expressed in Sf9 cells
Sinónimos:
3′,5′-cyclic-nucleotide phosphodiesterase, PDE 3B
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About This Item
Número MDL:
Código UNSPSC:
12352204
NACRES:
NA.54
En este momento no podemos mostrarle ni los precios ni la disponibilidad
Productos recomendados
recombinante
expressed in Sf9 cells
Nivel de calidad
Formulario
buffered aqueous solution
actividad específica
≥1000 units/μg protein
Condiciones de envío
dry ice
temp. de almacenamiento
−70°C
Aplicación
Phosphodiesterase 3B has been used in a study to evaluate the evidence for biological effects of metformin in operable breast cancer. Phosphodiesterase 3B has also been used in a study to investigate the role of intracellular and intercellular communication in perfusion distribution of erythrocyte-derived ATP.
Propiedades físicas
N-terminal GST-tagged 86 kDa protein containing amino acids 592-end
Definición de unidad
One unit will convert 1.0 picomole of 3′,5′-cAMP to 5′-AMP per minute at pH 7.4 at 37 °C.
Forma física
Buffered aqueous solution containing Tris-HCl (pH 8.0), NaCl, KCl, Tween-20, DTT, and glycerol
Código de clase de almacenamiento
12 - Non Combustible Liquids
Clase de riesgo para el agua (WGK)
WGK 2
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
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Lin Xie et al.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 18(4), 444-454 (2011-12-14)
Here we examined whether the expression of a novel immunoregulatory gene set could be used to predict outcomes in murine models of rapamycin-induced cardiac tolerance, spontaneous hepatic tolerance, and cardiac rejection. The expression of the immunoregulatory gene set was assessed
Randy S Sprague et al.
Microcirculation (New York, N.Y. : 1994), 19(5), 430-439 (2012-07-11)
In complex organisms, both intracellular and intercellular communication are critical for the appropriate regulation of the distribution of perfusion to assure optimal O(2) delivery and organ function. The mobile erythrocyte is in a unique position in the circulation as it
Sirwan Hadad et al.
Breast cancer research and treatment, 128(3), 783-794 (2011-06-10)
Metformin may reduce the incidence of breast cancer and enhance response to neoadjuvant chemotherapy in diabetic women. This trial examined the effects of metformin on Ki67 and gene expression in primary breast cancer. Non-diabetic women with operable invasive breast cancer
The cyclic AMP pathway.
Paolo Sassone-Corsi
Cold Spring Harbor perspectives in biology, 4(12), doi:10-doi:10 (2012-12-05)
Koji Ochiai et al.
Bioorganic & medicinal chemistry letters, 23(1), 375-381 (2012-12-04)
(-)-6-(7-Methoxy-2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-4-yl)-5-methyl-4,5-dihydropyridazin-3(2H)-one (KCA-1490) exhibits moderate dual PDE3/4-inhibitory activity and promises as a combined bronchodilatory/anti-inflammatory agent. N-alkylation of the pyridazinone ring markedly enhances potency against PDE4 but suppresses PDE3 inhibition. Addition of a 6-aryl-4,5-dihydropyridazin-3(2H)-one extension to the N-alkyl group facilitates both enhancement
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