D8821

Dextrano from Leuconostoc mesenteroides

average mol wt 60,000-76,000

• Fórmula lineal: (C₆H₁₀O₅)_n
• Número de CAS: 9004-54-0
• EC Number: 232-677-5
• MDL number: MFCD00130935
• UNSPSC Code: 12352201
• NACRES: NA.25

Propiedades

• biological source: bacterial (Leuconostoc mesenteroides)
• form: powder
• optical activity: [α]20/D 190 to 201 °, c = 2% (w/v) in water
• mol wt: average mol wt 60,000-76,000
• color: white to off-white
• mp: 483 °C ((901 °F ))
• solubility: water: 100 mg/mL at 25 °C, colorless to faintly yellow
• storage temp.: 2-8°C
• InChI: 1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2
• InChI key: FZWBNHMXJMCXLU-UHFFFAOYSA-N

Descripción

General description

Dextran is an extracellular bacterial polymer of D-glucopyranose. It consists of α-(1→6) linkage in the main chain with a variable amount of α-(1→2), α-(1→3), α-(1→4) branched linkages. Dextran from L. mesenteroides B512F comprises 95% of α- (1→6) linkages and 5% of α-(1→3) branch linkages. Insoluble dextran from L. mesenteroides 1299 contains 63% α-(1→6), 27% of α-(1→2) and 8% of α-(1→3) linkages.

Application

Dextran from Leuconostoc mesenteroides has been used:

• in resuspension of pellets and in Hanks′ balanced salt solution (HBSS) for the isolation of vascular nuclei from frozen post-mortem brain tissue
• to prepare dextran solution in phosphate buffer saline and to maintain corneal hydration and restore corneal thickness to physiological levels of human eyes
• as a polymer solution in the in situ aqueous two-phase systems (ATPS) formation with lysozyme PEGylation reaction

El uso de dextranos como brazos espaciadores largos e hidrófilos mejora el rendimiento de las proteínas inmovilizadas que actúan sobre las macromoléculas.

Biochem/physiol Actions

Dextran is commercially available as a drug, especially as a blood plasma volume expander. This bacterial polysaccharide has several applications, such as adjuvant, emulsifier, carrier, and stabilizer in the food, pharmaceutical, and chemical industries. Dextran is used in the thickening of jam and ice cream in the food industry. It prevents sugar crystallization and retains moisture. This helps in preserving the flavor and appearance of several food items.

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2