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Key Documents

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D6875

Sigma-Aldrich

21-Hydroxyprogesterone

≥97% (HPLC)

Sinónimos:

11-Deoxycorticosterone, 11-Desoxycorticosterone, 21-Hydroxy-4-pregnene-3,20-dione, 4-Pregnen-21-ol-3,20-dione, Cortexone, DOC, Desoxycortone, Kendall’s desoxy compound B, ‘Reichstein Q’

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About This Item

Fórmula empírica (notación de Hill):
C21H30O3
Número de CAS:
64-85-7
Peso molecular:
330.46
Beilstein/REAXYS Number:
2062123
EC Number:
200-596-4
MDL number:
MFCD00003661
UNSPSC Code:
12352200
PubChem Substance ID:
24894056
NACRES:
NA.77

biological source

synthetic (organic)

sterility

non-sterile

assay

≥97% (HPLC)

form

powder

solubility

ethanol: 50 mg/mL, clear, colorless to very faintly yellow

shipped in

ambient

storage temp.

room temp

SMILES string

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])C(=O)CO

InChI

1S/C21H30O3/c1-20-9-7-14(23)11-13(20)3-4-15-16-5-6-18(19(24)12-22)21(16,2)10-8-17(15)20/h11,15-18,22H,3-10,12H2,1-2H3/t15-,16-,17-,18+,20-,21-/m0/s1

InChI key

ZESRJSPZRDMNHY-YFWFAHHUSA-N

Gene Information

human ... SERPINA6(866)

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pictograms

Health hazard
GHS08

signalword

Warning

hcodes

H351,H373

Hazard Classifications

Carc. 2 - STOT RE 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Hirofumi Shibata et al.
Nature communications, 9(1), 2081-2081 (2018-05-29)
The faithful shutdown of the somatic program occurs in the early stage of reprogramming. Here, we examined the effect of in vivo reprogramming on Kras-induced cancer development. We show that the transient expression of reprogramming factors (1-3 days) in pancreatic
Nicola Craig et al.
Ecology and evolution, 7(16), 6201-6209 (2017-09-02)
Resource availability constrains the life history strategies available to organisms and may thereby limit population growth rates and productivity. We used this conceptual framework to explore the mechanisms driving recently reported negative relationships between fish productivity and dissolved organic carbon
J E Araújo et al.
The Science of the total environment, 687, 839-848 (2019-08-16)
The adverse effects of air pollution have been long studied in the lung and respiratory systems, but the molecular changes that this causes at the central nervous system level have yet to be fully investigated and understood. To explore the
Francesca Zalfa et al.
Cell death & disease, 8(11), e3169-e3169 (2017-11-17)
The fragile X mental retardation protein (FMRP) is lacking or mutated in patients with the fragile X syndrome (FXS), the most frequent form of inherited intellectual disability. FMRP affects metastasis formation in a mouse model for breast cancer. Here we
Dennis Gürgen et al.
Hypertension (Dallas, Tex. : 1979), 61(3), 730-736 (2013-01-23)
The deoxycorticosterone acetate (DOCA)-salt mouse model exhibits adverse cardiac remodeling in male mice and cardiac protection in female mice, even when blood pressure is normalized. We hypothesized that intact mammalian target of rapamycin (mTOR) signaling is necessary for cardiac protection
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