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C0125

Sigma-Aldrich

Cacodylic acid

≥98%

Sinónimos:

Dimethylarsinic acid, Dimethylarsonic acid, Hydroxydimethylarsine oxide

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About This Item

Fórmula lineal:
(CH3)2As(O)OH
Número de CAS:
75-60-5
Peso molecular:
138.00
Beilstein:
1736965
Número CE:
200-883-4
Número MDL:
MFCD00002095
Código UNSPSC:
12161700
ID de la sustancia en PubChem:
24892235
NACRES:
NA.25

Nivel de calidad

200

Ensayo

≥98%

Formulario

powder

solubilidad

water: 50 mg/mL, clear, colorless

cadena SMILES

C[As](C)(O)=O

InChI

1S/C2H7AsO2/c1-3(2,4)5/h1-2H3,(H,4,5)

Clave InChI

OGGXGZAMXPVRFZ-UHFFFAOYSA-N

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Categorías relacionadas

Palabra de señalización

Danger

Frases de peligro

H301 + H331,H350,H410

Clasificaciones de peligro

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B

Código de clase de almacenamiento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
MKCX0879
MKCV9107
MKCV9109
MKCT0098
MKCT4906

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Monika K Nisiewicz et al.
International journal of molecular sciences, 22(1) (2021-01-08)
Nearly half of patients with advanced and metastatic melanomas harbor a BRAF mutation. Vemurafenib (VEM), a BRAF inhibitor, is used to treat such patients, however, responses to VEM are very short-lived due to intrinsic, adaptive and/or acquired resistance. In this
Erik J Tokar et al.
Toxicology letters, 209(2), 179-185 (2012-01-11)
Inorganic arsenic, an early life carcinogen in humans and mice, can initiate lesions promotable by other agents in later life. The biomethylation product of arsenic, dimethylarsinic acid (DMA), is a multi-site tumor promoter. Thus, pregnant CD1 mice were given drinking
S Yamamoto et al.
Mutation research, 386(3), 353-361 (1997-06-01)
The modifying effects of dimethylarsinic acid (DMA), the major metabolite of ingested arsenicals in most mammals, on chemical carcinogenesis were investigated using rat in vivo models and reviewed here. In a multi-organ bioassay, rats pretreated with 5 carcinogens were administered
Hua Naranmandura et al.
Toxicological sciences : an official journal of the Society of Toxicology, 128(1), 137-146 (2012-04-28)
Arsenic is known to be a human carcinogen as well as one of the most effective drugs for treatment of patients with acute promyelocytic leukemia. The intermediate metabolites of arsenic, monomethylarsonous acid (MMA(III)) and dimethylarsinous acid (DMA(III)), are formed by
Hua Naranmandura et al.
Analytical and bioanalytical chemistry, 405(6), 1885-1891 (2012-06-27)
Arsenic (+3 oxidation state) methyltransferase (As3mt) plays a central role in the enzymatically catalyzed conversion of inorganic arsenic into methylated metabolites. Most studies of the metabolism and disposition of arsenicals following exposure to inorganic arsenic focus on the formation and
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