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B3398

Sigma-Aldrich

Anti-Human IgG2−Biotin antibody, Mouse monoclonal

clone HP-6014, purified from hybridoma cell culture

Sinónimos:

Monoclonal Anti-Human IgG2

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.46

origen biológico

mouse

Nivel de calidad

conjugado

biotin conjugate

forma del anticuerpo

purified from hybridoma cell culture

tipo de anticuerpo

secondary antibodies

clon

HP-6014, monoclonal

Formulario

buffered aqueous solution

reactividad de especies

human

técnicas

direct ELISA: 1:30,000

isotipo

IgG1

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

unmodified

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Descripción general

Monoclonal Anti-Human IgG2 (mouse IgG1 isotype) is derived from the hybridoma (HP-60141 ) produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. IgG is the most abundant serum immunoglobulins of the immune system. IgG2 is a subtype of IgG. IgG is secreted by B cells and is found in blood and extracellular fluids.

Especificidad

The antibody is specific for human IgG2 and is non-reactive with other IgG subclasses. This clone has been singled out as the most widely applicable IgG2 specific monoclonal antibody by the IUIS/WHO study.

Aplicación

Monoclonal Anti-Human IgG2−Biotin antibody produced in mouse has been used in indirect enzyme linked immunosorbent assay (ELISA) and immunoblot.

Acciones bioquímicas o fisiológicas

IgG provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.
Low IgG2 levels were found in patients with systemic lupus erythematosus (SLE) and juvenile diabetes melitus.

Forma física

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

nwg

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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